Not Hacker News Logo

Not

Hacker

News!

Home
Hiring
Products
Companies
Discussion
Q&A
Users
Not Hacker News Logo

Not

Hacker

News!

AI-observed conversations & context

Daily AI-observed summaries, trends, and audience signals pulled from Hacker News so you can see the conversation before it hits your feed.

LiveBeta

Explore

  • Home
  • Hiring
  • Products
  • Companies
  • Discussion
  • Q&A

Resources

  • Visit Hacker News
  • HN API
  • Modal cronjobs
  • Meta Llama

Briefings

Inbox recaps on the loudest debates & under-the-radar launches.

Connect

© 2025 Not Hacker News! — independent Hacker News companion.

Not affiliated with Hacker News or Y Combinator. We simply enrich the public API with analytics.

Not Hacker News Logo

Not

Hacker

News!

Home
Hiring
Products
Companies
Discussion
Q&A
Users
  1. Home
  2. /Discussion
  3. /Ticker: Don't die of heart disease
  1. Home
  2. /Discussion
  3. /Ticker: Don't die of heart disease
Last activity 15 days agoPosted Nov 8, 2025 at 9:59 AM EST

Ticker: Don't Die of Heart Disease

colelyman
600 points
488 comments

Mood

calm

Sentiment

mixed

Category

research

Key topics

Heart Disease Prevention
Healthcare
Medical Testing
Debate intensity70/100

The article 'Don't die of heart disease' provides a detailed guide to preventing heart disease, sparking discussion on the effectiveness of various prevention methods and the role of medical testing.

Snapshot generated from the HN discussion

Discussion Activity

Very active discussion

First comment

2h

Peak period

147

Day 1

Avg / period

40

Comment distribution160 data points
Loading chart...

Based on 160 loaded comments

Key moments

  1. 01Story posted

    Nov 8, 2025 at 9:59 AM EST

    19 days ago

    Step 01
  2. 02First comment

    Nov 8, 2025 at 11:37 AM EST

    2h after posting

    Step 02
  3. 03Peak activity

    147 comments in Day 1

    Hottest window of the conversation

    Step 03
  4. 04Latest activity

    Nov 11, 2025 at 11:51 AM EST

    15 days ago

    Step 04

Generating AI Summary...

Analyzing up to 500 comments to identify key contributors and discussion patterns

Discussion (488 comments)
Showing 160 comments of 488
camel_gopher
18 days ago
4 replies
Tl;dr be affluent enough to be able to afford great medical care and have enough free time for preventative actions
hshdhdhehd
18 days ago
1 reply
I think the point is it is cheap to prevent. The weird tip is doing a different test to the standard one, which costs little for typical HNers (but admit every $ counts for many people esp. with current inflation, poverty, bad governance) but sounds like on par with a dentist doing anything beyond a checkup.
lisbbb
18 days ago
A colleague of mine was a vegan, took care of himself, still died of pancreatic cancer. It is what it is.
tonymet
18 days ago
3 replies
Walking and eating sensibly is free. Even a balance oatmeal, rice & beans with infrequent meat servings would defend against heart disease better than expensive medicine, at less than $1 / day.
pstuart
18 days ago
2 replies
And not smoking or drinking saves you money!
tonymet
18 days ago
2 replies
nicotine is likely one of the best appetite-control , cognative-enhancing and anti-anxiety medications ever known to man. A large driver of obesity , anxiety and psychotropic abuse was smoking cessation.

Giving out nicotine gum , would decimate the drugs industry, but likely resolve a lot of our chronic health and depression issues.

64718283661
18 days ago
1 reply
I've actually considered taking nicotine for these reasons. But I don't because it appears you build tolerance very quickly.
tonymet
18 days ago
i know a number of people with moderate ADHD who use it instead of Adderall.
giardini
18 days ago
tonymet says >nicotine is likely one of the best appetite-control , cognative-enhancing and anti-anxiety medications ever known to man.<

Is this not under-reported? I have known several people for whom smoking appears to be truly necessary. One said he was prescribed smoking to control his "shakes".

gdulli
18 days ago
Yes, our system is most definitely stacked against the poor, but it's important to also remember that we all have free will and that some choices fully within our power are much better than others.
yinser
18 days ago
2 replies
Promoting good habits is good but this is health advice from an unlicensed commenter to say rice and beans is better than taking a statin. Consult your doctor if you’re curious what to do.
loeg
18 days ago
1 reply
Most people aren't on and don't need statins. Everyone would be well served to eat well and exercise regularly. It's not a replacement.
31carmichael
17 days ago
1 reply
You right. You don't need statins. Nobody does. But look at the statistics. You might also drop dead tomorrow. It's hard to know. If you think eating and exercising would solve heart disease, you are mis-informed. It's the number one killer. If we all died at 30, the drugs would not need to exist. I'm sure you would like to live as long as you can. Taking statins is cheap and simple for most people.
loeg
16 days ago
What are you talking about. People who need statins should take statins; this is informed by a basic metabolic panel, something every doctor does.
tonymet
18 days ago
It’s safer than taking unlicensed tech advice from an Internet forum
lotsofpulp
18 days ago
2 replies
Lentils/legumes are cheap. There is probably no better bang for the buck. Yogurt is also cheap.
giardini
18 days ago
1 reply
Funny you should use the word "bang". My last experiment with lentils years ago began one evening with 3 excellent bowls of very tasty lentil soup and ended slowly with 2 days' worth of "bangs", quickly followed by ostracism by my house buddies. So bad!
lotsofpulp
18 days ago
lol, you probably just need time for your gut bacteria to adjust. My family makes lentils for at least one meal almost every day.
tonymet
18 days ago
Agree. All the best foods are cheap. It’s a myth that healthy food is expensive. Most of the produce isle is decorative.
evantbyrne
18 days ago
1 reply
90 day supply of Atorvastatin costs $10. Running costs a pair of shoes.
camel_gopher
18 days ago
1 reply
You have to be able to get the prescription. HMOs (Kaiser specifically) will generally not provide any sort of preventative care in this area unless your numbers are very high. You can’t get access to a cardiologist unless you’ve already had an adverse event.

If you can get time off work and have a PPO, you can get the preventative care.

evantbyrne
18 days ago
$10 is the cash price. Your doctor diagnoses, not insurance, and you don't need a specialist to get diagnosed regardless of what your insurer wants. Even a nurse practitioner can prescribe you a statin.
adi4213
18 days ago
You should try www.betterbrain.com/insurance! It covers this set of bloodwork and 92% of covered patients pay $0
lateforwork
18 days ago
11 replies
The title of the article says "don't die of heart disease", but given that we all have to die at some point, if you could choose what natural cause to die of, wouldn't you pick heart disease? It is the best way to die. The worst is stroke. So once you cross a certain age, say 60, don't worry about heart disease, worry instead about stroke.
loloquwowndueo
18 days ago
1 reply
Why is heart disease a “good” cause of death?
lateforwork
18 days ago
1 reply
Less suffering. Stroke on the other hand... you become partially disabled, which causes suffering not just for you, but also for your loved ones.
poszlem
18 days ago
I think you are confusing "getting a stroke" and "dying from stroke". If you get a heart attack and don't die from it you might become a burden on your family too.
Avalaxy
18 days ago
1 reply
Funnily enough, the things you can do to prevent stroke line up entirely with the things you can do to avoid heart disease.
lateforwork
18 days ago
The article doesn't mention antioxidants at all, which help prevent atherosclerosis.
jpmattia
18 days ago
1 reply
> worry instead about stroke.

You say that as if stroke is orthogonal to heart disease. Much of what prevents one prevents the other.

lateforwork
18 days ago
Yes but there are habits that are especially important for preventing stroke, such as getting 7-9 hours of sleep, monitoring and controlling risk factors related to blood vessel health that affect the brain uniquely, such as preventing irregular heart rhythms (atrial fibrillation), anti-inflammatory diet choices focused on brain health, and so on.
DharmaPolice
18 days ago
1 reply
Dementia seems a pretty awful outcome too. I hope my heart gives out before my brain.
lateforwork
18 days ago
1 reply
Alzheimer's too.
sn9
18 days ago
If you made a Venn diagram for the non-genetic risk factors for heart disease and Alzheimer's, they'd basically be a circle.

Being worried about dementia but ignoring things like heart disease, diabetes, poor sleep, getting enough exercise, eating a health-promoting diet, etc. is like worrying about paying for retirement but refusing to save and invest.

There are a handful of high-impact habits that meaningfully lower your risk for the major killers people are worried about: https://www.barbellmedicine.com/blog/where-should-my-priorit...

masfuerte
18 days ago
If you have a massive banger and die immediately that is a pretty good way to go.

However, many people suffer from heart failure which, despite the name, means partial heart failure. The permanent breathlessness gives them a terrible quality of life. They can live with this for decades sometimes but it's not much fun.

Spooky23
18 days ago
I agree, but both are heart disease and both can be prevented in similar ways. My dad and my father in law both died from heart disease. My fil was on the surface less healthy. He had an extreme high stress job with exposures to environmental factors that made it worse, was partially disabled with bad knees, etc. i believe he was on blood thinners for almost 20 years.

He got up to make a sandwich for my mother in law, who was very sick, and don’t come back. Massive heart attack and aortic rupture - he was dead before he hit the ground.

My dad had a lot of stress over his career and his share of health issues but found a happy medium and improved his health greatly stating about in his late 40s. He was basically walk/running 2-5 miles a day for several years after retirement. He had a major stroke, recovered somewhat, and then ended up almost dying from a kidney stone and resulting infection. (He could not communicate pain as part of his aphasia.) long story short, he suffered in a lot of ways (pain, disability, loss of dignity) for 4 years before finally succumbing.

In online discussions, we tend to boil everything down to death. Reality is that longer you can put off complications, the better you will be when something more severe happens or you get sick. As you age, each time something happens, your recovery is a little less robust. Go to the doctor, take your statins and take care of yourself.

bluGill
18 days ago
What I want is a long life of doing what I want. when I must die how doesn't matter, but if I can extend my lifespan (well span) by not getting a heart attack that is good: more years to enjoy life. If I can also extend my life by not getting cancer even better. Even if I must die if I can delay that with a good life that is what I want.

note that I said good life. There are lots of bedridden people, I don't want to be like that. I want to be like the old person still doing things in old age.

derbOac
18 days ago
Sometimes I think the way this type of thing is framed is misleading. There's a list of putative causes of death and there's an assumption that they're equally systemically impactful, and you can go down the list and just lower the probability of each and lower your overall likelihood of death.

That's not totally off, but the thing about cardiovascular disease is it affects everything because it's how your body distributes oxygen. Stop distributing oxygen and you die.

That's not to say other organs aren't important, it's just that if you replace "cardiovascular" with "oxygen distribution" it becomes apparent that almost by necessity it's going to include a lot of deaths.

rufus_foreman
18 days ago
>> given that we all have to die at some point, if you could choose what natural cause to die of, wouldn't you pick heart disease?

Monty Python, "The Meaning of Life", Part VII.

jodrellblank
18 days ago
> "wouldn't you pick heart disease? It is the best way to die."

Dick Cheney (former USA Vice President) died a few days ago. Let's recap his publically known health:

- 1978 heart attack, age 37

- 1984 heart attack

- 1988 heart attack

- 1988 quadruple bypass surgery

- 2000 heart attack

- 2000 stent

- 2001 balloon angioplasty

- 2001 implantable defibrillator

- 2005 atery repair vascular surgery, stents behind the knees

- 2006 shortness of breath, hospitalized, blood clot

- 2006 travels everywhere with an ambulance standing by. Accidentally shoots friend. Friend has heart attack.

- 2007 deep vein thrombosis treatment, atrial fibrillation

- 2008 minor heartbeat irregularity

- 2010 January heart attack

- 2010 July Left-Ventricular Assist Device (LVAD) surgery for worsening congestive heart failure.

- 2012 heart transplant, cardiologist said "it would not be unreasonable for an otherwise healthy 71-year-old man to expect to live another 10 years".

- 2025 death, age 84, from complications of pneumonia and cardiac and vascular disease.

Or President Dwight Eisenhower:

- 1955 heart attack

- ? heart attack

- ? heart attack

- 1968 heart attack, heart attack, heart attack, heart attack

- 1968 cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest, cardiac arrest

- 1969 death from heart disease

Definitely not the best way to die. Heart disease is palpitations, fibrillation, chest pain, back pain, angina. It's leg swelling, breathlessness, dizziness, fatigue, slow wound healing. It's statins, beta blockers, stents, pacemakers, defibrillators, coronary bypasses, valve replacements, open heart maze scarring, angioplasty. It's not all widowmakers and sudden death. I would pick one of those "fell alseep and didn't wake up" things.

stavros
18 days ago
You assume that you'll die at X years old, and get to pick the disease. In reality, you might die of heart disease at 60, or cancer at 70, or alzheimer's at 80. Which one do you pick?
tonymet
18 days ago
3 replies
Fabulous information, but lacking information isn’t the issue. The behavioral changes are obvious and well evangelized : lose weight, regular activity (walking), and if necessary, take meds. (Yes I know your marathon runner cousin who died suddenly of a heart attack, but these are still your best odds)

Telling people what to do rarely fixes anything. People need dozens of impressions for those changes to sink in. Friends, family, social outings, commercials, movies, songs all promoting overindulgence won’t be overcome with a helpful pamphlet or nagging.

jasonjmcghee
18 days ago
1 reply
Managing stress shouldn't be overlooked
tonymet
18 days ago
2 replies
“Stress” is so abused and nebulous that it’s impossible to define. Nearly every condition is worsened by “stress” but there’s no way to measure it. And there’s no conclusive way to manage stress either. Medication, psychotropics, self medication, meditation. Nearly all of those are more broadly abused and yet stress “worsens”.

One person may run an intense soup kitchen 15 hours a day and feel little stress, and another can sit at a computer for 9 hours sending pointless emails and feel tremendous stress.

Jimmc414
18 days ago
1 reply
Managing cortisol shouldn't be overlooked
tonymet
18 days ago
1 reply
“Sleep better, eat better, get less stress, get more activity” is about as helpful as saying “don’t die”.
Jimmc414
18 days ago
True that “sleep better, eat better, exercise” is generic advice ignoring constraints. Like telling someone with insomnia, three kids, and a night shift to “sleep better” or telling someone broke to “have more money.”

But being difficult to put into action doesn’t mean the advice is wrong. Sleep deprivation measurably increases cortisol and inflammatory markers. Exercise measurably reduces them. These actions have quantifiable sometimes immediate effects regardless of how we define stress.

tananan
18 days ago
1 reply
Fortunately, as you mention in your last sentence, stress is introspectable.

How exactly stress corresponds to biomarkers doesn’t matter if your desire is to lower it.

The issue is that many of us don’t pay attention to how we keep our body & mind throughout the day, or do so on a very superficial level. So strain on the body can accumulate for a long time.

“Stress management” is a lifetime skill. It doesn’t come in bulletpoints, it’s as broad as “living happily”.

Edit: That said, this can make the advice “be less stressed” a bit vacuous.

But people do get scared when random health issues flare up and become more conscious of how they deal with stress in life.

So it’s not bad to keep reminding people either :)

tonymet
18 days ago
it’s bad in the way of “don’t think about elephants” makes you think about elephants.

“Try not to stress” or “reduce stress” – but how to do that? Stress itself is nebulous, and the countermeasures are inconclusive.

Think of the last time you were angry or frustrated. Did your spouse telling you to “calm down” fix the problem?

lotsofpulp
18 days ago
1 reply
> The behavioral changes are obvious and well evangelized : lose weight, regular activity (walking), and if necessary, take meds.

More specifically, it’s “change your diet and eat/drink less”, which is the hardest part. Diet’s impact eclipses regular activity, and it’s consequences build up and compound over decades.

tonymet
18 days ago
i agree. Under-eating with baseline activity is better than overeating with excessive activity, excluding the extremes.
Zak
18 days ago
1 reply
This site isn't necessarily meant to have a big sociological impact; it provides enough information that someone with sufficient motivation, but a lack of resources and expertise can take concrete steps to reduce their risk. That seems useful to me.
tonymet
18 days ago
in this case “useful” means applying the facts and making changes. A detailed map that goes unused is useless. A hand drawn map that gets you home is priceless.

People don’t need more facts and information – those are in surplus. In fact, for most people when they receive too many facts, they just glaze over.

The changes needed are trivial

cogman10
18 days ago
3 replies
I might just be tired, but this seems highly repetitive. The author mentions friends in the field and concierge doctors multiple times in as much as I read.

Feels like the whole thing could be shortened to just say "here's the tests you run, the drugs you might take, the lifestyle changes you should consider".

rustman123
18 days ago
3 replies
It’s also demonizing doctors and the healthcare system a bit too much for my liking.

I’m located in Europe, so I may have a slightly different view, but my doctors clearly care and discuss with me about prevention, risks, tradeoffs, …

They praise the methods of the „good“ doctors and stamps the others as driven by financial gain. Who says the expensive ones are any better in this regard? Who says they are more or less exaggerating the importance of test results to make you come back?

lotyrin
18 days ago
In the US my best doctors produce out of date advice about obvious things, have a very distinct gap between "everyday" (stuff they actually see) and "incredibly rare" (stuff unique enough to be a case study they heard about) in their knowledge/understanding and rarely advise things that require me to be a proactive and rational person (because they don't serve these often), so they'll spend two seconds being like "diet and exercise" without a discussion on how that'd work or what adjustments I'd actually make (leaving me to do this research myself) and then suggest a prescription (because even their least proactive patient will probably take a pill). They'll wait until things become a disorder before addressing them (or discussing with me how to address them).

The worst will basically laugh me out of their office for daring to belong to a marginalized identity or failing to already have the health knowledge I'm there trying to gain from them.

Maybe I have awful luck... but I have very little faith at this point. The most effective relationship I had was with a hack who was willing to just prescribe whatever I asked him for and order whatever tests I asked him for (I think most of his patient base were college students seeking amphetamine salts).

bluGill
18 days ago
I'm in the us and my doctors have all done the same. Though it is obvious most people are not listening to them.
rootusrootus
18 days ago
I'm in the US, and my experience has been similar. My doctor is good, and while we're usually limited to 30 minutes at my appointment, we have good conversations and rarely is his answer "here is another pill" or "go take this random test."
Scubabear68
18 days ago
Somewhat related, one of my thoughts was “what if these concierge doctors just keep running tests until they find something, anything, to justify their fees”?
naIak
18 days ago
Right? It started okay even if a bit too verbose, then there was a second introduction. There I lost interest.
hackama
18 days ago
4 replies
Very interesting, but do the numerous mentions of taking action in your 20s, 30s and 40s mean it's too late for someone in their 50s?

Nitpick: he mentions LDL-C but the test results don't mention that at all. Only later do I see that is "LDL Cholesterol".

johnrob
18 days ago
1 reply
If you start exercising in your 20s, and never stop, it will be so much easier to maintain fitness in 40s 50s etc. The challenge is that the benefits are not yet visible in your 20s (when you’ll probably be healthy and at a proper weight regardless). Gotta lay that foundation for older age though!

EDIT - I misread the comment. It’s never too late to start, just be careful for injuries as that will block your ability to exercise.

HPsquared
18 days ago
It's a bit like saving money.
daveguy
18 days ago
No, it is never too late to take action. Even taking action after a stent procedure reduces further risk:

https://www.nhs.uk/conditions/coronary-heart-disease/treatme...

sn9
18 days ago
It's like time in the market.

In a real sense, you've spent decades likely increasing your risk unnecessarily when taking action early would have given you the greatest leverage to lower your lifetime risk.

But you can't change the past. If you didn't plant a tree 20 years ago, plant it today and you'll still get some benefit, minimizing any future increase in risk and maybe even lowering it.

You could realistically have almost half your life left before you, and you can still end up being fitter and healthier than you've ever been in your life if you adopt healthy habits around diet, strength training, and endurance training.

arjie
18 days ago
In general, when science is done, recruitment requirements force the experimenters to bucket the participants. One thing that often happens is an open bucket, say 35+.

The resulting science is then reported as “When you cross 35, your chances of being pregnant immediately drop” or “The brain stops developing at 18” and so on.

Almost nothing in the body is really like this, though. You can quit smoking later in life and it will help. You can eat better later and it will help. You can exercise and it will help. Very few things are “the damage is done”.

The only constraints are that the later you start the more risks you face. E.g. if you first deadlift in your 50s and you decide to follow Starting Strength you’re going to have trouble.

k__
18 days ago
2 replies
There doesn't seem to be any mention of hypertension on that page.
Zak
18 days ago
1 reply
If you're going to press ctrl+f and post a critique, I recommend including a synonym or two in your search terms.
jeffbee
18 days ago
As much as the HN trend is against AI features in client software, this is an excellent use of Gemini-in-Chrome. Instead of wracking your brain for English synonyms, you can just ask it if the page discusses hypertension, a kind of weapons-grade ctrl+f. Mine said

"Yes, the article discusses hypertension, referring to it as "high blood pressure.""

fullStackOasis
18 days ago
1 reply
Actually, there is. You have to search for "pressure". For example, "Other Tests: There are some other things that are important to know as well. You must know your blood pressure".
k__
18 days ago
Good point.

I've forgotten that blood pressure is another word for it, as all medical papers use hypertension.

Thanks!

pstuart
18 days ago
2 replies
A key takeaway is: don't be afraid of taking statins if you need them. I fell for the "statins are bad" BS for years and have paid the price.
Buttons840
18 days ago
1 reply
What price have you paid?
pstuart
18 days ago
1 reply
I now have a cardiologist and just had an MRI to check on the state of my aorta, as a recent calcium scan brought up concerns.

I've now been on rosuvastatin and ezetimibe for several years with zero noticeable negative effects. I'm hoping that this with other behavior modification can help stave off further damage for a while.

31carmichael
17 days ago
I recommend the same. There are other interventions, but these two medications are straightforward to obtain with low or no side effects.
lisbbb
18 days ago
2 replies
My dad would disagree--he's 84, was on statins for years and they did terrible things to his body. I'm sure the drugs kept him alive, but the side effects, as he describes them, particularly to his legs and kidneys, were pretty severe. He only got better when he stopped taking them.
Buttons840
18 days ago
1 reply
I believe statins reduce risk by about 30%, so there's a roughly 30% chance the statins have done good things for your dad.

(I think that's what the stats mean, right? I'm open to correction on this. I do believe the statin studies, I'm not a science denier. I think what I've said matches the science, as far as I understand.)

AstroBen
18 days ago
1 reply
The risk reduction is relative risk not absolute
Buttons840
17 days ago
You're right. The absolute risk reduction would be more appropriate here.
pstuart
18 days ago
Obviously we all differ in how we respond to medications -- apparently it's 10% - 15% that have issues with statins.

I think a pragmatic approach would be to try them if warranted by testing and be prepared to stop or change them if it has issues.

We're learning more and more about the mechanisms of cholesterol and there's a variety of medications out there: https://www.heart.org/en/health-topics/cholesterol/preventio...

And that doesn't address the role that fiber plays in managing it (and the virtues of fiber for health in general that are coming to light at a rapid clip)

dawnerd
18 days ago
3 replies
Was this written via LLM? There’s a link early on to some ai search tool which kinda made me question the validity of everything mentioned.
OutOfHere
18 days ago
3 replies
Please strictly cease and desist from accusing material of being written by an LLM, whether on this site or on any other site. If you want to criticize the material, do so under the good faith assumption that it is written by a human.
dawnerd
18 days ago
2 replies
I think it’s absolutely fair to criticize something for potentially being generated via an llm or heavily utilized by such especially when it comes to medial claims.

Reading it I couldn’t help but feel the author relied on ai research tools and is now passing that along to everyone reading as if it’s proven fact. When they link out to an ai search engine that’s not helpful when trying to cite sources.

stavros
18 days ago
We don't really know the author. For all I know, the LLM is more accurate than the specific human, in which case I'd want the article to be written by an LLM.

Saying "LLM bad, human good" is both false and uninteresting.

OutOfHere
18 days ago
No. It is false criticism. It is like calling one a witch in historical times. Anyone gets accused of it without hard evidence. For all I know, your comment was AI generated. You relied on AI and are now passing that along. It's not helpful.
floundy
18 days ago
1 reply
Genuinely, why? More people than ever are using LLMs to flood the internet with textual slop far faster than humans who have respect for the craft of writing can generate their own text.

I checked Jared Hecht (the author of this piece’s blog) at jared.xyz and the oldest piece is from March 2023. Why should we give someone who has no evidence of writing anything before the release of ChatGPT the benefit of the doubt that their work is all human written, when all signs point to otherwise?

OutOfHere
18 days ago
1 reply
Because the signs are only in your head. There is no hard evidence. It is a disingenuous and false way to attempt to discredit someone. Anyone can be accused of it for writing anything at all. The argument that the writing started after the invention of ChatGPT is simply horrible because everyone starts sometime.

It's like calling someone a witch in historical times. By the way, your comment looks to be AI generated, so please do us a favor and stop generating more slop.

floundy
18 days ago
1 reply
Of course there is no "hard evidence" unless someone leaves evidence of the prompt or AI response in their blog post. There are certain clues and syntax. Your comment seems like it would fit in much better on Reddit than on HN.
OutOfHere
18 days ago
Negative. You're the one making unproven bad-faith assertions, trying to discredit someone on the basis of witch-hunting logic. Your comment belongs nowhere.
loeg
18 days ago
It's a wall of poorly written text. Whether it was a human or LLM is kind of not the main problem.
esseph
18 days ago
You should always have questioned the validity, but now you feel the need because of LLMs.
jeffbee
18 days ago
It has many markers of that, including being about ten times longer than it needed to have been.
AaronAPU
18 days ago
4 replies
I was planning to start getting scans ordered for specific risks like aneurysm or heart attack but what holds me back is the idea the scans will harm me worse than those things.

It is very difficult to have any level of confidence with the medical industry so my current approach has been to eat as healthy as possible while staying as fit as I can without undue extreme stress.

rogerrogerr
18 days ago
2 replies
As someone who would like to do this but has generally been choosing the easy paths - curious what your diet and exercise regime looks like.
sn9
18 days ago
There are specific recommended minimums in the physical activity guidelines about strength training and endurance training where meeting them is likely to significantly reduce your disease risk and improve your health: https://www.barbellmedicine.com/blog/where-should-my-priorit...
AaronAPU
18 days ago
Well “fortunately” I’m forced to have a strict diet due to some sort of IBS issues. For that, I use the MacroFactor app and talk through my daily recipes with ChatGPT, making sure to hit the macros and calories targets while also optimizing for heart health and IBS. Fat, protein, carbs, fiber. Taking AG1 to fill gaps.

For fitness I’m obsessed with biking so I do like 90 minutes of endurance/tempo pace 5 days a week and usually a race once a week. Zwift is great with a Tacx when weather is bad (often).

That isn’t a time option for everyone but it is also likely well beyond what is necessary for most people.

I also don’t drink or smoke or vape which I think is important.

Not going to say I’m an expert or an exemplar of health but I am really trying everything I know to do at this stage.

captainkrtek
18 days ago
3 replies
A relevant anecdote. I’m very athletic and skinny, eat well, have a resting heart rate in the 40s, but was recently prescribed a statin at 30, due to my very high LDL cholesterol and lipoprotein A.

My family has a history of cardiovascular disease despite us doing what we can w.r.t eating and exercise. I’d encourage you to get some tests at least.

My mother similarly was put on statins and is getting a cardiovascular work up (calcium scan) because she now has early atherosclerosis. She eats super healthy and is a former olympic sprinter..

Bonus anecdote: In my free time I do shifts as an EMT with my fire dept (911), that is a big wake up call to wanting to be as healthy as can be. The number of patients I see who are 50+, nearly all are on 5-10+ meds, few are just one 0, 1, or 2. At that age I see type 2 diabetes, hypertension, high cholesterol, and more.

AaronAPU
18 days ago
1 reply
They have me on blood pressure meds and do the usual blood tests, the tests I considered have been elective and I requested them explicitly. Just haven’t followed through due to aforementioned hesitations. I’m very much aware heart issues run in the family and that I have symptoms.

But I would be very happy to do any elective non invasive tests. On the fence about going beyond that until/unless the Dr. flags it as needed.

captainkrtek
18 days ago
That makes sense! Its easy I think to also go overboard and analyze too much, causing stress as you suggest.
guerby
18 days ago
1 reply
You're probably a "lean mass hyper-responders", a phenotype which is actively investigated, initial paper:

Elevated LDL-cholesterol levels among lean mass hyper-responders on low-carbohydrate ketogenic diets deserve urgent clinical attention and further research

https://pubmed.ncbi.nlm.nih.gov/36351849/

A few other more recent papers:

https://pubmed.ncbi.nlm.nih.gov/35498420/

https://www.jacc.org/doi/10.1016/j.jacadv.2024.101109

Note: I'm not a doctor.

captainkrtek
18 days ago
Interesting, thanks for sharing!
rootusrootus
18 days ago
Seems a bit unfair sometimes how arbitrary genetics can be. I've fought my weight all my life, only recently achieving consistent success with the assistance of GLP1s. I can't claim to be consistent with exercise either. Yet my numbers are great, I've done some of these deeper tests and everything comes back beautiful. My parents were overweight their whole life and both lived deep into their 80s (and my dad only died because he got an unlucky gall bladder infection and then ignored all the rapidly accumulating evidence that he was getting quite sick; he'd have gone another few years most likely). I don't recall anyone in my immediate ancestors having a heart attack. Seems it's just not in our genetics.

My father-in-law is more like you. Athletic, skinny, been that way all his life. Heart attack and quad bypass in his 40s.

JoshTriplett
18 days ago
> scans will harm me worse than those things

There are two known harms from scans:

- Radiation. This is why people shouldn't get these scans several times a year, but 1-2 are very unlikely to move the needle. The average radiation from a full chest CT is just under the average dose for ~2 years of normal background radiation. (I don't know if a CTA uses less than average.)

- Acting on something you would otherwise have ignored, where ignoring it might have been the right answer. The main problem here is that it's hard to get a medical opinion saying "you should ignore this" because of perverse incentives: there's an aversion to recommending doing nothing because that could lead to a lawsuit, whereas "overtreatment" will not get a doctor sued. However, you can make a deliberate decision to do this anyway even after getting the scan; seek second and third opinions, consider alternatives, weigh risk versus reward, make a considered decision.

sn9
18 days ago
Health guidelines take into account when screening/testing is a net harm or benefit for patients in general, and when they move from being a net harm to a net benefit conditional on specific factors like existing diseases, obesity, etc.

Any decent doctor should be at least following those, and you can pretty easily find them from the major disease-focused organizations.

Importantly, there are also recommendations for how often you see a doctor based on things like age and known disease risk. You might discover you have risk factors that are genetically resistant to lifestyle factors, and the earlier you find out, the more leverage you have to decrease your lifetime risk with appropriate medication.

I'd check out the Barbell Medicine podcast episode on the health priorities they recommend patients focus on: https://www.barbellmedicine.com/blog/where-should-my-priorit...

lbrito
18 days ago
2 replies
I don't like this kind of content. The author might have a personal motivation for it, but for the general public, it's just more mental load.

We are all going to die one day.

When I was younger, I would fret over this kind of article. Great, one more thing I have to worry about. Now I just mostly ignore it. It's impossible otherwise. If I dedicate hours and days and months to all the heart best practices, what about when the liver, esophagus, kidney, bladder, brain articles come out?

We all know the good practices. Don't be a dumbass. Don't drink too much, exercise and so on. Besides that, I'm very much going to be reactive, as the article cautions against. I just don't have time or mental energy to do otherwise.

bwfan123
18 days ago
> We all know the good practices. Don't be a dumbass

In theory yes, but in practice we are all dumbasses to some extent.

I used to have your attitude until I saw a friend die of a heart attack at an early age - and it appeared to me that he would have survived if he had an indication. So, now I have changed my attitude to one of more data does not hurt.

bbor
18 days ago
I share your general emotional reaction, but to be fair, heart disease is far and away more important than other type of disease. More people die of it in the US than die of all cancers combined: https://www.cdc.gov/nchs/fastats/leading-causes-of-death.htm
potato-peeler
18 days ago
1 reply
The value of the biomarkers are they applicable for all age range? What if someone already had a heart attack, then what should be the normal values post incident?
themk
18 days ago
AFAIU, for LDL and ApoB, the real danger lies in the area under the curve. Lifetime exposure. That's not to say that lifestyle improvement can't help in other ways, but the damage caused by LDL is very difficult (impossible) to reverse.

So, if you hit the point where you already had a heart attack, you really want to prevent any further damage, but the "accumulated" risk is still there.

I think that's part of what makes LDL so tragic. You should care about it your whole life, but when you are young, you just don't.

Worse, high LDL is becoming a thing in children as well, that's an extra decade of accumulation which has historically not happened.

I don't think people should panic about these things, but I think it highlights the importance of developing good habits early, and the role parents and society has in making those habits easy for young people to adopt.

zamiang_brennan
18 days ago
3 replies
Great post but quite surprised there is no mention of cutting red meat. There is a lot of evidence that especially the American diet is dangerously high in red meat to the point of elevating Heart Disease risk.
mac-mc
18 days ago
1 reply
IMO, I think that is more of a saturated fat issue, and only a subset of the population is like that. Others solve their health issues through eating a lot of red meat.
sn9
18 days ago
1 reply
Yeah it's definitely more about saturated fat from animal sources.

A leaner cut like tenderloin is fine.

Ultimately you just want to keep the calories you get from saturated fats from animal sources to less than 10% of your daily calories. You can still enjoy a nice steak or burger every once in a while, but they shouldn't be a daily staple if health is a priority.

mac-mc
17 days ago
1 reply
No, I mean for some, a high saturated fat diet can do amazing wonders. And for others, it causes horrible issues. The studies are not well segmented genetically and by body state since that is signficantly more expensive and genetics only got cheap in the past 10 years or so, so they wash out these large sub-population dynamics.
sn9
17 days ago
It's the sort of thing you can just experiment with and see for yourself.

Try eating the usual health-promoting diet high in fiber and low in saturated fats from animal sources, mostly whole foods, lots of fruits and veggies and legumes and whole grains, lean meats, etc.

After a few months, check your blood work.

Then reintroduce fattier cuts of meat into your diet and see what your numbers do after a few months.

zoeysmithe
18 days ago
1 reply
Also processed red meats or processed meats in general. Processed meats are the ones strongly linked with heart disease. At least for those who dont want to go vegetarian.

Processed meats are so bad, they should be eliminated entirely from everyone's diet. The World Health Organization has classified processed meat as a Group 1 carcinogen. No amount of it is considered safe.

Unprocessed read meat is still a problem and WHO advises less than 350g a week. Which is 12–18 ounces of cooked meat. 12g is about one adult serving of steak. So you really are looking at 1.5 servings per week of unprocessed red meat to be safe. At most! You probably should try for less or closer to 12g.

And really if you're at a healthy weight, then I'm not sure how helpful this is. Obesity is a bigger risk factor. This is a bit of the elephant in the room for heart health. Not only should we not be eating things associated with heart disease but also we need to keep ourselves at a healthy weight.

fcpk
18 days ago
these are extremely outdated recommendations that make no sense. most of the basis for those are studies that took direct correlation as causality. the problem is a crappy lifestyle which incidentally typically includes processed and red meats in large quantities in the western world. saturated fats are hardly a good indicator of anything when you disassociate them from the lifestyle and foods they come with for most people. blue zones are now finally coming out as simply just the places where records sucked. there are plenty of populations with centenarians that had meat rich diets.

yes obesity is bad, as the source enemy of most diseases that kill and are not cancer is inflammation. find a diet that makes you not obese and have low inflammation, that is vastly superior to "Mediterranean diet" or "plant diet" for everyone.

ekianjo
18 days ago
Especially the red meat pumped up with hormones...
throwaway89201
18 days ago
2 replies
I'm not sure that non-medically indicated CT scans are a great idea, as you're at least doubling your yearly dose of radiation in the year of the CT scan. Perhaps it's warranted, but the article doesn't seem to balance that at all against doing a CT scan "every 1-5 years".
dumbmrblah
18 days ago
1 reply
I agree. As a physician, this is sticking out to me as bad / dangerous advice. By getting unneeded regular CT scans, you’re dramatically increasing your risk of developing cancer. Beyond the radiation exposure itself, there is also the very real possibility of incidental findings that can lead to further testing, invasive biopsies, and unnecessary interventions, all of which compound your overall risk. You might solve one problem, but you’ve just guaranteed a much bigger, more explosive one down the line.
bluGill
18 days ago
You won't die of heart diesease if you die of cancer first. So I guess it sortof checks out, but not what I would choose.
Esophagus4
18 days ago
Yes - in addition, medical professionals warn against “overdiagnosis” from unnecessary screenings.

This can happen when we choose to treat otherwise benign issues that would have had few negative consequences for our health or longevities. Those treatments can have negative effects that are worse than the ailment we’re trying to treat.

I know it’s a natural tech-guy impulse to quantify everything and get access to as much data as you can, but that myopic focus can actually lead us to optimize for the wrong thing.

[1]https://pmc.ncbi.nlm.nih.gov/articles/PMC4077659/

[2]https://pmc.ncbi.nlm.nih.gov/articles/PMC6135119/

carbocation
18 days ago
4 replies

    Key Takeaway: Get a CT or CTA scan, and if you can afford it go for the CTA with Cleerly.
There is a reason that we don't recommend getting imaging for everyone, and that reason is uncertainty about the benefit vs the risks (cost, incidentalomas, radiation, etc, all generally minor). Most guidance recommends calcium scoring for people with intermediate risk who prefer to avoid taking statins. This is not a normative statement that is meant to last the test of time: it may well be the case that these tests are valuable for a broader population, but the data haven't really caught up to this viewpoint yet.
safety1st
18 days ago
9 replies
Right.

Hang on a second.

This guy is making a big big claim.

The central point of his article is that he went to a doctor who followed the guidelines, tested him and found he wasn't at risk for heart disease.

But then he went to another, very expensive concierge doctor, who did special extra tests, and discovered that he was likely to develop heart disease and have a heart attack.

Therefore he is arguing that THE STANDARD GUIDELINES ARE WRONG AND EVEN IF YOU DO EVERYTHING RIGHT AND YOUR DOCTOR CONFIRMS IT YOU MAY BE LIKELY TO DIE OF HEART DISEASE ANYWAY, SO ONLY THE SPECIAL EXTRA TESTS CAN REVEAL THE TRUTH.

I want a second opinion from a doctor. Is this true? Is this for real? Because it smells funny.

malfist
18 days ago
2 replies
His evidence is also kinda weak. And appeal to authority largely about someone who he's paying to tell him he has health problems. The incentives aren't aligned.

I also disagree that the 50the percentile is the breakpoint between healthy and unhealthy. There's a lot more to deciding those ranges beside "well half of the population has better numbers"

kelipso
18 days ago
1 reply
ApoB is a better indicator of heart problems and his ApoB was bad, unlike his LDL-C. ApoB is not some imaginary thing made up by a quack doctor.
cthalupa
18 days ago
1 reply
Even his LDL-C is bad. 116/119 are both out of range by most lab testing standards and the top end of range already allows for plaque deposition.
kelipso
17 days ago
1 reply
That LDL-C is considered normal, what are you talking about. 160 is when doctors start being concerned.
cthalupa
15 days ago
That is an out of range value for the two largest testing labs in the USA - Quest and Labcorp. Their upper end is 100.

https://testdirectory.questdiagnostics.com/test/test-detail/...

https://www.labcorp.com/tests/120295/low-density-lipoprotein...

If you think a 100+ LDL-C is normal you're basing things off of significantly outdated information.

Expect the normal range to drop in the coming years as well - the AHA and NLA have both been talking about how this needs to go lower, and the science is robust. See my other comments for study links, the NLA's latest guidance, etc.

If your doctor is only getting concerned at 160+, find a new doctor.

wrs
18 days ago
2 replies
You may have missed the stat that 30% of the population that’s the median of will die of heart disease. You don’t want to be at the median.
rgmerk
18 days ago
1 reply
100% of the population will die of something.

If I die at 90 of a heart attack havjng maintained the ability to live independently up until then, I’d take that as a massive win compared to my relatives suffering through a decade of me with worsening dementia.

ac29
17 days ago
Cardiovascular diseases are huge risk factors for dementia, so if your goal is to avoid dementia you should try to have a healthy cardiovascular system.
malfist
18 days ago
If health science was as simple as health outcomes are proportional to one or two measurement percentiles, sure. But that's hardly true. Health is a lot more complex than that and the disease risk cannot be quantified by a small number of parameters
sixtyj
18 days ago
1 reply
If there are two contradictory conclusions you should ask for the third one, independent on the previous ones.
Apes
18 days ago
2 replies
The year is 1846, and a doctor has a radical new idea: doctors should wash their hands between performing autopsies and delivering babies!

You're not sure of whether this is a good idea or not, so you ask various physicians, and the consensus is unanimous: the very suggestion is offensive, do you think doctors are unclean?

A clear conclusion has been achieved.

paxys
18 days ago
Are you implying that every new, unproven idea is a good one?
sixtyj
18 days ago
You’re right. My comment doesn’t make sense.
Apes
18 days ago
2 replies
I strongly suspect the truth is both are "right", but they're both optimized answers to slightly different problems.

Mainstream medicine is hyper optimized for the most common 80% of cases. At a glance it makes sense: optimize for the common case. Theres some flaws in this logic though - the most common 80% also conveniently overlaps heavily with the easiest 80%. If most of the problems in that 80% solve themselves, then what actual value is provided by a medical system hyper focused on solving non-problems? The real value from the medical system isnt telling people "it's probably just a flu, let's just give it a few days and see" it's providing a diagnosis for a difficult to identify condition.

So if your question is "how do we maximize value and profit in aggregate for providing medical care to large groups of people", mainstream medicine is maybe a good answer.

But if your question is "how do we provide the best care to individual patients" then mainstream medicine has significant problems.

fwip
18 days ago
1 reply
Part of providing good care is not burdening the patient with tests or treatments that are very unlikely to yield benefit. Put another way, the mission of healthcare is not "health at any cost."
embedding-shape
18 days ago
1 reply
The mission of healthcare in the eyes of those who provide it, isn't "health at any cost".

For the people on the other side, "health at any cost" is pretty much the goal, usually limited by the "cost" side of things, especially in the parts of the world where they haven't yet figured out the whole "healthcare for the public" thing.

fwip
18 days ago
Cost here doesn't just include financial cost, but also time. As an extreme example, you could surely catch diseases earlier by visiting a doctor for an hour or two every day - getting tests for all sorts of things you might have conceivably developed. But that would make your life worse, and so most people wouldn't do that even if it was free.
6510
18 days ago
The actual question should be "how do we have the fewest patients"
cthalupa
18 days ago
1 reply
The National Lipid Association and American Heart Association have both been advocating that lower cholesterol numbers are better, e.g. https://www.lipidjournal.com/article/S1933-2874(25)00317-4/f...

Research science in this area has been in agreement for a long time now that ApoB is a more informative indicator than just LDL-C, because there are a variety of different atherogenic particles, not all LDL particles are created the same, etc.

His ApoB numbers are quite readily and apparently out of range. Hell, even his LDL is out of range for the two largest lab providers in the US - Labcorp and Quest both have <100 for their reference range. But the science shows that plaque progression is still generally occurring at levels above 70 LDL-C even with low Lp(a) and other atherogenic particles - the reference ranges are likely to get moved lower and lower as practice catches up with research.

His numbers are well within the range of concern based on pretty universal consensus across the research in this area over the past couple of decades. Preventative cardiologists and lipidologists would almost certainly agree with this concierge doctor.

safety1st
17 days ago
1 reply
Thanks for the astute and informed comment. So re-reading that portion of the article, it seems to me the answer to my question is not that any general or consensus guidelines are wrong, but that a company called Forward Health is doing lipid panels and providing an incorrect interpretation of the results.

OP's LDL-C was 116 and this is on the very top end of what Forward Health's report says is OK, their report is wrong, this number is bad.

All the stuff about needing to measure ApoB, needing a high end concierge doctor, and the very long article about measuring 10-20 different numbers and doing more exercise than the guidelines and being at risk of heart attack if you don't do amounts of exercise that the author consider unreasonable etc., some of this may have value, but this all seems to be a lot of very lengthy personal opinion by the techbro author of the post. The key insight is simply that your LDL-C becomes a cause for concern over 100, perhaps even over 70, and he was not as healthy as some tech company told him he was. No surprise there, I will talk to actual doctors instead of using services from "tech forward" startups any day of the week.

cthalupa
17 days ago
1 reply
I would agree that this article overstates a lot of things.

ApoB is still a reasonable thing to check though, at least once - Lp(a) is the primary cause of atherogenic particle counts being high when LDL-C isn't the culprit, and it's usually a genetic factor. Having a high Lp(a) will bounce your ApoB up and give you a better understanding of the total atherogenic particle load. You could have fine LDL-C or Lp(a) on their own but the total amount could be enough to be worrisome.

Lp(a) being problematic is definitely less common than it being more or less fine, but it's certainly not incredibly rare, either.

safety1st
16 days ago
Really great context, thanks!
bsder
18 days ago
The plural of anecdote is not data.

Maybe he got missed--let's concede that. What about the other 10 or 100 or 1000 or subjected themselves to tests and didn't find anything? Where are their stories?

If you have enough people, the tests, themselves are eventually going to harm somebody.

For example, certain scans require contrasts like gadolinium that bioaccumulates. That's not a big deal if we only pump it into people 2 or 3 times in their lives when something in their body is about to explode. It's a lot bigger deal if we're doing that to them every year.

antonvs
18 days ago
We went through this with Oprah in 2007. She did a show about her CT scan and how wonderful it was.

Here's what the New York Times had to say about it the following year: https://www.nytimes.com/2008/06/29/business/29scan.html

The bottom line is these tests aren't some sort of one-size-fits-all panacea, and nor can they perfectly predict the future. In fact Oprah herself backtracked on it, via an article by Dr. Oz in her magazine in 2011: https://www.oprah.com/health/are-x-rays-and-ct-scans-safe-ra...

A good rule of thumb is don't take medical advice from Oprah or Dr. Oz. But in the case of the latter article, he wasn't wrong.

Aurornis
18 days ago
> But then he went to another, very expensive concierge doctor, who did special extra tests, and discovered that he was likely to develop heart disease and have a heart attack.

It’s scarily common in medicine for doctors to start specializing in diagnosing certain conditions with non-traditional testing, which leads them to abnormally high diagnosis rates.

It happens in every hot topic diagnosis:

When sleep apnea was trending, a doctor in my area opened her own sleep lab that would diagnose nearly everyone who attended with apnea. Patients who were apnea negative at standard labs would go there and be diagnosed as having apnea every time. Some patients liked this because they became convinced they had apnea and frustrated that their traditional labs kept coming back negative, so they could go here and get a positive diagnosis. Every time.

In the world of Internet Lyme disease there’s a belief that a lot of people have hidden Lyme infections that don’t appear on the gold standard lab tests. Several labs have introduced “alternate” tests which come back positive for most people. You can look up doctors on the internet who will use these labs (cash pay, of course) and you’re almost guaranteed to get a positive result. If you don’t get a positive result the first time, the advice is to do it again because it might come back positive the second time. Anyone who goes to these doctors or uses this lab company is basically guaranteed a positive result.

MCAS is a hot topic on TikTok where influencers will tell you it explains everything wrong with you. You can find a self-described MCAS physician (not an actual specialist) in online directories who will use non-standard tests on you that always come back positive. Actual MCAS specialists won’t even take your referral from these doctors because they’re overwhelmed with false cases coming from the few doctors capitalizing on a TikTok trend.

The same thing is starting to happen with CVD risks. It’s trendy to specialize in concierge medicine where the doctor will run dozens of obscure biomarkers and then “discover” that one of them is high (potentially according to their own definition of too high). Now this doctor has saved your life in a way that normal doctors failed you, so you recommend the doctor to all of your friends and family. Instant flywheel for new clients.

I don’t know where this author’s doctor fits into this, but it’s good to be skeptical of doctors who claim to be able to find conditions that other doctors are unable to see. If the only result is someone eating healthier and exercising more then the consequences aren’t so bad, but some of these cases can turn obsessive where the patient starts self-medicating in ways that might be net negative because they think they need to treat this hard to diagnose condition that only they and their chosen doctor understand.

carbocation
18 days ago
The claim on an individual level is not objectionable to me. The question is that if we extrapolate it out to the population and actually take this action for everyone, do we make people better off? This is what clinical trials (or at least large observational studies) try to achieve. Right now, it is not clear.
rasse
18 days ago
It's important to note that there's geographic variability in guidelines. Also, the article doesn't give enough information about the author's other risk factors. For a similar patient (based on the initial lab results), treated by a doctor adhering to the European guidelines, at least the following items would have been considered:

- Lipid lowering drugs

- ApoB testing

- Coronary CT (if the pre-test likelihood of obstructive coronary artery disease was estimated to be > 5%)

- Diabetes tests

- Kidney tests

doganugurlu
18 days ago
1 reply
Not sure I follow or maybe you skipped typing a word.

You listed the risks and concluded “all generally minor.” The benefit is absolutely nonzero. So, what’s the hold up?

And how have the data not caught up? People outside the US are getting the CT scans, while US doctors prefer to lick their finger to guess the weather.

My wife’s last interaction with a doctor: patient presents with back and chest pain accompanied by occasional shortness of breath at the age of 39, doctor reluctantly asks for a EKG - which takes 5-10 minutes and is done in the next room, right away and covered by insurance with a small copay - and has the gall to be surprised when EKG showed subtle abnormalities. If she hadn’t advocated for herself, as the OP argues, doctor would just skip the EKG.

This experience left me thinking maybe doctors are discouraged from asking for imaging and guidelines are there to protect their criminally negligent behavior. I have no proof or even proxy data for the claim about doctors being discouraged from asking for imaging. But it is objectively criminally negligent to not ask for imaging in a case like this.

moralestapia
18 days ago
"Smaht" people continuously parrot things they read elsewhere, usually in a contrarian way, to assert themselves in a futile and shallow way.

There is absolutely nothing wrong with getting one CT at a specific point in your life to right a disease which, as TFA states, has a 25% incidence rate.

The smaht ones will now point me to that study of 1-5% of cancers being linked to CT scans. Yeah, sure, but those are not from people who got one-two in their lives.

IshKebab
18 days ago
That seems like a super dumb reason to me. "We don't look because we might misinterpret the results"?? Fix the interpretation then!

It's crazy that we haven't optimised MRI scans so that they can be routine.

jbritton
18 days ago
A CIMT scan is another option. It uses ultrasound to measure carotid artery wall thickness.
Buttons840
18 days ago
1 reply
I am not a statin skeptic--or rather, I don't want to be a statin skeptic. I've done the research and it makes sense to me, but I still feel some social and psychological pressures to reject statins.

When I see that it is widely accepted that ApoB is better to measure than LDL-C, but the industry continues to measure LDL-C, but not ApoB, I wonder why. It makes me skeptical.

When I see that the purpose of statins is to reduce plaque buildup in the arteries, and that we have the ability to measure these plaque buildups with scans, but the scans are rarely done, I wonder why. Like, we will see a high LDL-C number (which, again, we should be looking at ApoB instead), and so we get worried about arterial plaque, and we have the ability to directly measure arterial plaque, but we don't, and instead just prescribe a statin. We're worried about X, and have the ability to measure X, but we don't measure X, and instead just prescribe a pill based on proxy indicator Y. It makes me skeptical.

In the end statins reduce the chance of heart attack by like 30% I think. Not bad, but if you have a heart attack without statins, you probably (70%) would have had a heart attack with statins too. That's what a 30% risk reduction means, right?

As you can see, I'm worried about cholesterol and statins.

mac-mc
18 days ago
If you fix it without statins through better lifestyle and diet, that is the preferrable route.

As to why medicine is like this, it's because it's conservative, usually about 17 years behind university research[0], and doctors are shackled to guidelines in most health systems or risk losing their licenses. It isn't a coincidence that the article author had his out-of-pocket concierge doctor tell him the more up-to-date stuff.

[0] https://pmc.ncbi.nlm.nih.gov/articles/PMC3241518/

qgin
18 days ago
I love this sort of documentation-style guide to medical issues. Reminds me of https://www.fourmilab.ch/hackdiet/e4/
lisbbb
18 days ago
Love the chart at the bottom--it really puts on display media bias and lack of integrity and using fear to push idiotic policies which area really just a way to put everyone in the pocket of government and keep them there permanently with zero real improvement to public health. Fear get eyeballs. the Covid mass hysteria proves that, too.

As far as heart disease goes, yes, it's the big killer and it's time people started waking up from the media haze, but to do that, you have to admit you were wrong, and for many, that is far too tall a hill to climb.

hshdhdhehd
18 days ago
It is a long read and I want to make time for it. Quick search check and calc (for calcify etc.) and diet appear alot in the article which is not surprising based on other things I have watched on the subject.
FlamingMoe
18 days ago
I recently did a comprehensive panel of my own volition with Quest Labs and was pleasantly surprised by the entire process. It was super easy to schedule, affordable, and their online platform is surprisingly sleek.

328 more comments available on Hacker News

View full discussion on Hacker News
ID: 45857053Type: storyLast synced: 11/22/2025, 11:47:55 PM

Want the full context?

Jump to the original sources

Read the primary article or dive into the live Hacker News thread when you're ready.

Read ArticleView on HN
Not Hacker News Logo

Not

Hacker

News!

AI-observed conversations & context

Daily AI-observed summaries, trends, and audience signals pulled from Hacker News so you can see the conversation before it hits your feed.

LiveBeta

Explore

  • Home
  • Hiring
  • Products
  • Companies
  • Discussion
  • Q&A

Resources

  • Visit Hacker News
  • HN API
  • Modal cronjobs
  • Meta Llama

Briefings

Inbox recaps on the loudest debates & under-the-radar launches.

Connect

© 2025 Not Hacker News! — independent Hacker News companion.

Not affiliated with Hacker News or Y Combinator. We simply enrich the public API with analytics.