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  3. /Cocoa's Flavanols Protect Blood Vessels From Uninterrupted Sitting
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  3. /Cocoa's Flavanols Protect Blood Vessels From Uninterrupted Sitting
Nov 22, 2025 at 7:51 PM EST

Cocoa's Flavanols Protect Blood Vessels From Uninterrupted Sitting

giardini
6 points
2 comments

Mood

informative

Sentiment

positive

Category

research

Key topics

Health

Nutrition

Research

Wellness

Discussion Activity

Light discussion

First comment

27m

Peak period

1

Hour 1

Avg / period

1

Comment distribution4 data points
Loading chart...

Based on 4 loaded comments

Key moments

  1. 01Story posted

    Nov 22, 2025 at 7:51 PM EST

    1d ago

    Step 01
  2. 02First comment

    Nov 22, 2025 at 8:18 PM EST

    27m after posting

    Step 02
  3. 03Peak activity

    1 comments in Hour 1

    Hottest window of the conversation

    Step 03
  4. 04Latest activity

    Nov 23, 2025 at 3:55 AM EST

    22h ago

    Step 04

Generating AI Summary...

Analyzing up to 500 comments to identify key contributors and discussion patterns

Discussion (2 comments)
Showing 4 comments
giardini
1d ago
1 reply
Save your ass: make yourself a cup of cocoa!

FTFA:

"Forty young healthy men, 20 who had higher levels of fitness and 20 who had a lower level of fitness, consumed either a high-flavanol (695 mg of total flavanols per beverage) or low-flavanol cocoa drink (5.6 mg of total flavanols per beverage), before completing a two-hour sitting trial."

That last-highlighted phrase is you every day!

https://contentbash.com/who-are-butthole-surfers-facts-songs...

Butthole surfers - Pepper:

https://www.youtube.com/watch?v=KRXty8lDUW0

ksaj
22h ago
Not sure how the Butthole Surfers relate (the name, I guess), but I used to listen to them a lot in the 90's. There was a period where their name was considered "too offensive" and their album sleeves were labeled "B.H. Surfers" which just makes the whole thing more comical.
rixed
1d ago
1 reply
> This is the first time flavanols have been shown to be effective at preventing sitting-induced vascular dysfunction, in young healthy men.

How many times did they try before? Am I right to suspect p-hacking?

giardini
23h ago
See earlier work, e.g., https://pmc.ncbi.nlm.nih.gov/articles/PMC3835452/

FTFA (2008) ABSTRACT:

"The Kuna Indians who reside in an archipelago on the Caribbean Coast of Panama have very low blood pressure levels, live longer than other Panamanians, and have a reduced frequency of myocardial infarction, stroke, diabetes mellitus, and cancer -- at least on their death certificates. One outstanding feature of their diet includes a very high intake of flavanol-rich cocoa. Flavonoids in cocoa activate nitric oxide synthesis in healthy humans. The possibility that the high flavanol intake protects the Kuna against high blood pressure, ischemic heart disease, stroke, diabetes mellitus, and cancer is sufficiently intriguing and sufficiently important that large, randomized controlled clinical trials should be pursued.".

View full discussion on Hacker News
ID: 46019717Type: storyLast synced: 11/23/2025, 7:38:58 AM

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