Key Takeaways
Coincidentally, I published a paper in the Journal of Neuroscience during my PhD demonstrating with a simple mathematical model how E/I balance enabled neurons to be highly sensitive to precise spike timing. [2]
(Or hodgkin-huxley with fewer)
A show-HN mid-dive with Brian simulator would be cool
In contrast GABA and glutamate mainly just handle the general information processing across the entire brain, there isn't a whole lot to do other than inhibit GABA which happens to reduce anxiety (as well as your entire brain's cognitive health)
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