How does 3' to 5' translation of circular RNAs work?
molecular biologyRNA translation
The user is inquiring about the translation of circular RNAs (circRNAs) in the 3' to 5' direction.
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Circular RNAs (circRNAs) are a class of RNAs that form a covalently closed loop. The translation of circRNAs is an area of ongoing research. While most translation occurs in the 5' to 3' direction, there is evidence that some circRNAs can be translated in a non-canonical manner. However, translation in the 3' to 5' direction is not typically associated with circRNAs or most other RNAs, as the standard genetic code and translation machinery operate in the 5' to 3' direction.
Key Takeaways
circRNAs are covalently closed loop RNAs
Non-canonical translation of circRNAs is an area of ongoing research
Standard translation occurs in the 5' to 3' direction
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