Twins Reared Apart Do Not Exist
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The notion that twins reared apart are a myth has sparked a lively debate about the validity of twin studies, particularly those exploring the heritability of IQ. Commenters are divided, with some arguing that twin studies are flawed due to the complexities of human reproduction and the limitations of aggregate data, while others insist that genetics play a significant role in determining traits like IQ. As the discussion unfolds, it becomes clear that the disagreement isn't just about the science, but also about the desire to draw socially palatable conclusions from the data. The debate is heating up, with some commenters accusing others of being driven by ideology rather than a genuine pursuit of understanding.
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In other words - Junior should not be presumed to be smarter, fitter, more deserving, or destined for success, just because his parents did well. No matter how attractive that conclusion might sound, to people who consider themselves to be the "better" sort.
success has components of luck as in "right place, right time" for someone with the right qualities and connections, and many of the very successful are quick to admit this
I am a 3rd generation machinist along the paternal line, and although the machines I operate are in expensive labs, those my father and grandfather operated were probably just as challenging. Engineering also seems to often run in the family. How much is nature and nuture? "It varies" is a safe response
Epigenetics of Intelligence
Epigenetics plays a significant role in shaping human intelligence by dynamically regulating gene expression without altering the underlying DNA sequence This process acts as a bridge between genetics and environmental influences, allowing factors such as diet, stress, exercise, sleep, and social interactions to influence cognitive abilities like memory, focus, reasoning, and learning Epigenetic mechanisms include DNA methylation, histone modification, and non-coding RNA regulation, which function as molecular switches to turn genes on or off, thereby affecting brain development and function
Research indicates that epigenetic changes can impact key genes involved in cognitive performance. For instance, polymorphisms in the DNMT3L gene have been associated with childhood intelligence scores, with the minor T allele linked to higher cognitive ability Similarly, epigenetic modifications in the DRD2 gene, which is involved in dopamine neurotransmission, have been shown to correlate with general IQ in adolescents, highlighting the equal importance of genetic, epigenetic, and functional brain markers in cognitive performance Furthermore, methylation in the INPP5A gene has been linked to cognitive ability and hippocampal volume, suggesting a direct connection between epigenetic regulation and brain structure
Environmental factors such as education, nutrition, stress, and trauma can induce epigenetic changes that either enhance or impair cognitive function Chronic stress, for example, can lead to DNA methylation that suppresses genes related to focus and reasoning, impairing mental clarity Conversely, positive environments—such as those rich in learning opportunities and emotional support—can promote epigenetic marks that boost neural plasticity and cognitive potential The rapid increase in average IQ scores observed over the past century, which cannot be explained by genetic evolution alone, is thought to be partly due to environmentally-induced epigenetic changes
Importantly, epigenetic modifications are potentially reversible, offering opportunities to improve cognitive abilities through lifestyle interventions. Regular exercise, a nutrient-rich diet, stress management techniques like mindfulness, quality sleep, lifelong learning, and strong social connections have all been shown to positively influence epigenetic profiles and support brain health While epigenetic changes in the brain are most relevant to intelligence, inherited epigenetic marks from germ cells may also contribute to intergenerational cognitive traits, although this remains an area of active research
In summary, epigenetics provides a crucial framework for understanding how intelligence develops through the interaction of genes and environment, with implications for cognitive enhancement and mental health
https://hn.algolia.com/?dateRange=all&page=0&prefix=false&qu...
"That is, once you include the rare variants, the amount of genetic variation that “should” exist but doesn’t shrinks to only 12%. Plausibly an even bigger study, investigating even rarer variants, could shrink the gap further, all the way to zero."
https://theinfinitesimal.substack.com/p/the-missing-heritabi...
The problem is most people's zealous desire to read socially self-serving conclusions into any data they can find on such subjects. And when they really like the Q.E.D. punchline, humans have very low standards for the "logic" used to reach it.
what planet are you living on?
also your comment was completely incorrect and missing the entire point of twin studies. When corrected you didnt stay quiet, apologise or say thanks, you continued pretending you were making a different point.
Noone is going probably going to read this comment apart from you, Im giving you some feedback.
The truth is, for these kinds of studies, the whole enterprise might as well be metaphysical; people saying these kinds of things have formed a religious conviction about the heritability of behavioral traits, and their real objection is that science continues to be done on the topic at all. Ironic, given the frequency with which they complain that this science is suppressed.
(I too have a near-religious conviction about this subject, though in a different direction; I do not, however, pretend that conviction is itself a methodological critique!)
Whether or not you like MISTRA, “they left out the non-identical twins” is a side issue, and the broader evidence that IQ is substantially heritable is extremely strong.
Even if DZA were excluded, MZA alone provides a solid heritability estimate. The DZA sample was small and noisy, and MISTRA uses other twin and family data. Plus, meta-analyses confirm high IQ heritability, typically 0.5-0.8; Later structural-equation models applied to the full MISTRA cognitive dataset (MZA + DZA) estimated the heritability of general intelligence around 0.77, essentially the same ballpark as the original simple estimate. laplab.ucsd.edu. Intelligence is highly heritable, potentially reaching 80% in adulthood, supported by further studies like the Haworth et al. meta-analysis, showing age-related increases in heritability.
Strong evidence for polygenic and SNP heritability is shown from Plomin & von Stumm's 2018 research, showing how polygenic scores predict general intelligence.
Adoption studies further support the genetic influence, as adoptive siblings show weaker correlations compared to biological ones.
Environment is certainly NOT outweighed entirely or beyond merit, but evidence clearly shows the "uncomfortable" result having strong support despite desperate attempts to debunk.
In short; the op's story only works if including the DZA data actually drags the heritability estimate down into trivial territory. It does not.
Later analyses of the MISTRA sample that explicitly include both MZA and DZA twins and use full structural-equation models estimate heritability of general intelligence (g) at about 0.77 in adults. https://laplab.ucsd.edu/articles2/Lee2010.pdf
That is higher, if anything, than the original approximate 0.70. In other words:
The alleged “suppressed control group” does not turn the result into “no heritability”.
The more sophisticated models using that very same DZA data still say “IQ differences in this adult sample are heavily genetic.”
You just don't like this data, and don't want to accept it, because of the implications.
As it happens, I often run into trouble due to my conceptualist views on the foundations of mathematics (that is, I'm a hardcore physicalist & anti-Platonist cognitivist, which is quite rare among mathematicians), so I find your criticism particularly unfair.
created: 1 day ago
karma: -3
everything you need to know in a nutshell. username itself even has an implication.
"Whether or not you like MISTRA, “they left out the non-identical twins” is a side issue, and the broader evidence that IQ is substantially heritable is extremely strong.
Even if DZA were excluded, MZA alone provides a solid heritability estimate. The DZA sample was small and noisy, and MISTRA uses other twin and family data. Plus, meta-analyses confirm high IQ heritability, typically 0.5-0.8; Later structural-equation models applied to the full MISTRA cognitive dataset (MZA + DZA) estimated the heritability of general intelligence around 0.77, essentially the same ballpark as the original simple estimate. laplab.ucsd.edu. Intelligence is highly heritable, potentially reaching 80% in adulthood, supported by further studies like the Haworth et al. meta-analysis, showing age-related increases in heritability.
Strong evidence for polygenic and SNP heritability is shown from Plomin & von Stumm's 2018 research, showing how polygenic scores predict general intelligence.
Adoption studies further support the genetic influence, as adoptive siblings show weaker correlations compared to biological ones.
Environment is certainly NOT outweighed entirely or beyond merit, but evidence clearly shows the "uncomfortable" result having strong support despite desperate attempts to debunk.
In short; the op's story only works if including the DZA data actually drags the heritability estimate down into trivial territory. It does not.
Later analyses of the MISTRA sample that explicitly include both MZA and DZA twins and use full structural-equation models estimate heritability of general intelligence (g) at about 0.77 in adults. https://laplab.ucsd.edu/articles2/Lee2010.pdf
That is higher, if anything, than the original approximate 0.70. In other words:
The alleged “suppressed control group” does not turn the result into “no heritability”.
The more sophisticated models using that very same DZA data still say “IQ differences in this adult sample are heavily genetic.”
You just don't like this data, and don't want to accept it, because of the implications."
"For some people some subjects take on an irrational religious experience. Anything that is not a forceful agreement must be destroyed." Disagreement is not against the rules. Flagging a comment simply because you disagree with the content does appear to be against the rules, however, based on my reading.
The evidence is overwhelming in that direction:
Twin & family designs: h² ~0.4–0.8, often ~0.7–0.8 in adult samples like MISTRA.
Adoption: people resemble their biological relatives more than their adoptive relatives in IQ, despite strong environmental differences.
Molecular genetics: polygenic scores and GCTA show real, replicable genetic signal for intelligence.
What it does not mean is that:
1. IQ is fixed at birth in a way that cannot be influenced by environment.
2. IQ differences justify any sort of discrimination or moral ranking.
Those two points are where people tend to clutch their pearls and panic. Just because we have noticed an uncomfortable truth does not mean that it is valid to use it in a discriminatory manner; the issue becomes that people will inevitably do so, thus those "in power" cripple the theory in the crib so as to avoid the fearful and uncomfortable implications.
It's practically nobody's position that there's no linkage between genetics and intelligence (that would be weird indeed), but it's important for this comment for you to believe that's the counterargument --- otherwise the comment doesn't make sense.
If genetics is less than 5 percent I would consider that something worth ignoring.
If it is 10 percent it is substantial enough to make a difference at the extremes.
If it is 20 percent that is real serious business.
Anything higher means we should really sit up and take notice of this fact.
If you're arguing against a eugenicist then it's not just about the percentage, in that case you have to distinguish between genetic and heritable. Suppose that there are some set of four genes that, in just the right combination, are worth 5 IQ points. That's, by definition, genetic, but it won't have a strong correlation with heritability because every kid has four chances to get the combination wrong. Or, if the combination does something bad, four chances to get it right even if their parents didn't. So past performance is no guarantee of future results.
By contrast, if you're trying to decide whether to allocate more resources to kids who already show promise, you care about the individual's natural potential rather than the statistical probability that it will be similar to their parents. And by the point you're performing the evaluation, you can't go back in time and change things like the prenatal environment for someone who is already born, so in that context those things belong in the "nature" column and "nurture" only gets the things you could still affect.
Let the science science, and policy makers make policy.
I think the problem comes when we want scientists to make policy recommendations.
I think scientists should help us determine what the facts are, not decide what to do about them.
What to do is for courts and democracy and for individuals to decide?
> 50% may sound like a solid heritability figure, but the associated correlation is rather modest.
Now the substance:
"The alleged “suppressed control group” does not turn the result into “no heritability”."
=> Of course not, did anyone claim there was no heritability? But
1/ It's not "alleged", it's printed black on white in the paper.
2/ There is no excuse for suppressing control group data (it's like suppressing the placebo arm of a drug study).
3/ It does turn the result into "junk", and it does establish a definite case of scientific malpractice among people arguing that IQ heritability is 0.70.
As for later analyses, they weren't the topic of my post, but that doesn't mean they're casher.
"I don't care if you find it fair. If you can't accept that genetics determines the entire organism (stress: entire) and does not stop at the neck, then you'd perceive my later criticisms as much worse than - gasp! oh great heavens! my pearls! - unfair. It is a bitter pill to swallow that some people were simply born with better hardware than yourself, one you are obviously railing against. Now, rush on and down vote this comment as well to lighten the burden of your cognitive dissonance. I'm also finding it difficult to reconcile your use of the flag/report on the parent comment versus the rules dictating and describing what is disallowed content. Disagreement is not against the rules. Perceived "fairness" is not in the rules."
Sorry to inform you that you don't understand the meaning of the verb "determine", as "genetics determines the entire organism" is scientifically wrong for obvious reasons: "influences", yes; "encodes proteins for", yes; but "determines", no.
And, no, I'm not railing against anyone's hardware as I'm pretty satisfied with mine.
Ironically IQ is also popular amongst people in a very different situation, that is, people that aren’t actually successful “in the real world” but score highly on aptitude tests. Their high scores serve as an identity pedestal to look down upon others and set themselves apart from the masses. This seems to be the primary demographic of IQ-requirement organizations.
Now of course there are scientific studies on this topic, but let’s not pretend like this is a cultural meme because writers like Cremieux are just tirelessly searching for the truth, no matter what ideological consequences that may have. They quite obviously have a viewpoint first and then work backwards from there to justify it.
As a meta comment: the whole obsession with IQ as a kind of unchanging permanent quality seems very much out of tune with how biological systems actually work, and is kind of a remnant of a Platonic worldview. That is, it’s not dynamic/process/system oriented in the way that nature actually works, but instead is in search of eternal qualities á la Plato.
Being smart is a poor proxy for success, you have to have access to the right knowledge and resources at the right time, and often the “smart” move is short term.
It could be argued (and often is), that the reason intelligence is strongly predicted based on heritage (though of course: not guaranteed) is due to your parents interactions with you as a child.
like many things, I’m not qualified to answer.
Sufficed to say that some of the smartest people I personally know are more limited in their success than some of the confident yet much less intelligent people I know: who seem to be, in general, much more successful.
It also gives some valid argumentation to people who promote race theory... which is, obviously, a racist ideology.
That said, the experiences of my youth in animal husbandry make me a strong believer in genetic determinism.
It is empirically practical to use breeding alone to predict cognitive abilities, behaviors, tendencies, and elicitable capabilities in animals, given identical rearing environments. Right down to nervous ticks, inherent fears, very specific nuisance behaviors, as well as predictable desirable behaviors, dispositions, and fascinations. Even preference for certain types and even colors (shades?) of toys over others. The fine grained nature of determinism in behavioral tendencies is remarkable.
There is so much overlap of structure and function within mammals that it is extraordinary to claim that apes are somehow exceptional by categorically fundamental properties rather than degree.
Great apes are much more adaptable and capable than most animals, and environment probably plays a much greater role in our development because of the power of our faculty for learning, but that does nothing to negate the underlying heritability of extremely fine grained cognitive traits.
Animals are in no way blank slates when they are born. Genetic or in-utero programming plays a huge role in cognitive processes, and cognitive capacity is a direct dependent of physical structure.
One does not predict the other necessarily, but there is still a difference between a partially full mug and an overflowing shot glass, even if they hold the same volume in practice.
We are born with unequal capacities in both physical and cognitive realms. It is an uncomfortable truth. We do ourselves a disservice when we try to pretend inconvenient things are not so just so we don’t have to face uncomfortable choices.
It doesn't require any such thing. It doesn't take a super genius to understand the roles of chance and circumstance have on one's lot in life.
There aren’t a lot of billionaires out there acting in a way that shows this. At best, they give the idea some lip service.
What would that be?
From there, the sky is the limit. Directly helping underserved communities access the same networks/resources is another. A handful of billionaires have also donated their entire wealth, but the laudability of that depends on your ethical stance of course.
That someone could be a billionaire, spend their time writing essays about how inequality is good, retweet and give attention to people insisting that intelligence and success are mostly inheritable – and yet also deeply understand that their success is largely dependent on chance? Uh, I guess such a person could exist, but it seems like you’re just nitpicking here.
And of course there is an obvious ethical claim here: that people who benefit from a system and become wealthy should feel some sort of ethical obligation to contribute to or improve access to that system. Or at least not actively try to deny that such a system helped them. This is a complicated topic which is why I said “depending on one’s ethical views.”
No idea what my personal situation has to do with this, but I assure you, I’m not a billionaire, nor am I wealthy, unless merely being born in a Western country implies that one is wealthy (a nonsensical claim.)
What’s particularly annoying is that this can so easily be proven false. No amount of heritable IQ points are gonna help if you’re born to a starving family escaping genocide in Sudan.
But also, “IQ” has been a useful characteristic for a few decades to maybe a few centuries at most. For most of human existence, pure physical strength was likely much more useful than the ability to do abstract thinking.
So even if we accept all these easily disproven ideas, it’s still clearly evident that the fact that they’re in a position to benefit from these supposedly heritable traits is only because they happen to be extremely fortunate to be born in a time and place where these traits are actually valuable.
Several 9s of humans that ever existed would have found an Einstein level of genius worthless
Substituting "generations" for "9s", whatever that is...
Citation needed.
How do you know it didn't take Einsteinian-level intelligence to first make the leap that fire can be controlled, or flint knapped, or ochre used to paint images?
I've never understood the idea that winning the genetic lottery somehow makes a person more "deserving" or "worthy" than another. To me, the whole idea of "meritocracy" is a moral abomination.
Ideally everyone would get the same chances to do valuable things but that's not how the world is setup. Unfortunately.
However trying to change that must be done with care as it's easy to increase injustice (looking at most communist systems)
I'm not fond of the term "rewarded." I understand how prices are determined by supply and demand in economics. Obviously in the labor market, some skill that is in high demand and/or short supply will bring a high price. However, economics are largely amoral. The economic system is not an ethical system to reward the worthy and punish the unworthy, just a method of distributing resources.
There's both an uncontroversial and a controversial interpretation of "meritocracy." Uncontroversially, those who are best qualified for a job should do that job, especially for life-and-death jobs like in medicine. This is how the argument usually starts, with the uncontroversial interpretation, but then it slyly shifts to the controverisal interpretation, that certain people "deserve" more money than others, often a lot more money, due to the qualifications. And while we may want economic incentives for the most qualified people to persue certain jobs, overall it doesn't appear to me that the economic incentives align with societal benefit. For example, we massively reward professional athletes and entertainers much more than doctors and nurses.
Ultimately, the controversial notion of meritocracy is used to justify enormous disparities of wealth, where some people have so much money that they can buy politicians and elections, whereas others are so poor that they have trouble affording the basics like food, shelter, and medical care.
I agree that that could be a motivation. But I would also say that having a motivation for a given result doesn't preclude that result. That is generally true in science.
I'm not an expert. But there seems to be fairly overwhelming evidence that some significant amount of intelligence is heritable. That IQ is a reasonably good measure (or proxy) for intelligence. And that IQ correlates well with a lot of other things like educational attainment and income.
That doesn't mean that your genes determine your future. But it does suggest that some people are "born" in a better position than others -- aside from their socio-economic status.
This shouldn't be controversial. Height is well-known to be heritable. Being tall gives you a better shot at making the NBA. The same is true for many other things.
I don't understand why so many commenters here are arguing against a straw man. The article author does not and never did believe in the "blank slate" theory.
The author is critiquing hereditarians, not blank-slatists. (To be clear, the author is not defending blank-slatists, if any actually exist.)
> The author has a "centrist" view that genes matter but are not the only determining factor.
Nobody thinks genes are the only determining factor (that's a straw man on the other side :)
Most people agree it is somewhere on a continuum. Some people think it leans more one way; others the other way. Some people want it to lean more one way; others want it to lean more the other.
How so? You said, "This shouldn't be controversial. Height is well-known to be heritable. Being tall gives you a better shot at making the NBA. The same is true for many other things." But there's no indication that the previous comment was arguing the opposite of that. Rather, the previous comment was arguing against this idea: "Surely success and intelligence is just an inborn thing, and thus inevitable and unchangeable. There’s nothing they can do, and it was always going to end up that way. Inevitability erases any feelings or guilt or shame."
I'm sorry if I didn't get my point across in a way that satisfies you. But I suggest you take a step back and re-read what both of us wrote. Or maybe just move on.
My understanding is that the author thinks the heritability of IQ is somewhere between 30% and 50%, but not 80% or 100%, and not 20% or 0%.
Being able to correctly say, for instance, which of four options a "façade" is most like has nothing to do with inherent intelligence; it has to do with whether you were taught the meaning of the word "façade", and the four (often somewhat uncommon) words presented as the choices. The same is true for any of the questions that are, even in part, testing your vocabulary.
Presenting such a test to two people, one of whom was educated at a private school in New York City, and came from a family that highly valued reading and education, and the other at a public school in rural upstate NY, and came from a family that thought it was "too woke" for boys to read books, it is painfully obvious which one will do better, regardless of any genetic factors.
Also count me in for disallowing childless people in many of societies political leadership positions. A position I would have found ludicrous 10 years ago. ;)
It’s just not possible to understand the best way forward for the species if you haven’t procreated.
Then there's a category of people who resent their children and younger generations generally.And another category of childless idealists who feel protective of humankind and the planet as a whole. Would you approve the resentful and deny the idealists?
The idea seems pretty flawed and unjust...
Why would you decide to hold a position strongly based on a minuscule and extremely biased sample set and reject even considering data and studies outside of your immediate experience?
Unless you’re afraid your conclusion might be challenged? Wouldn’t it be interesting either way? Either to find out that your children are typical or to find out that you and they are special in some way?
I understand many people are not interested in or curious about science, but don’t understand people who are both disinterested but also strongly hold particular positions on scientific questions.
Isn't your question exactly that addressed by the (admittedly too long) article? That the graph Paul Graham presented proving the dominance of inheritance wasn't based on any science or data?
There are many studies of twins that try to determine if genes influence intelligence.
Some look at twins who are raised together. One [1] concludes that "MZ (identical) twins differ on average by 6 IQ points, while DZ (fraternal) twins differ on average by 10 IQ points". (Did they control for sex / gender ??)
[1]: https://pmc.ncbi.nlm.nih.gov/articles/PMC6202166/
Yes? I mentioned them because the article was about a bunch of studies? I was asking the poster why you would not be interested in the validity of such studies and just decide that "common sense" was enough to make a decision?
The question was asked with genuine curiosity as this forum is mostly filled with people who appreciate science and empiricism. And I was hoping there could be a reasonable discussion.
But I'm out. An interesting discussion should be possible here purely based on data and statistics but clearly - from the downvotes - that I've stepped into some toxic American identity politic minefield.
I learned quite a time ago that it's risky to raise certain scientific subjects with USAians including my US relatives: biological evolution, the science of climate change, renewable energy or justifications for gun control - without the conversation getting emotional and heated. But I still find it weird.
Centuries of success with empirical based science is a direct rejection of the approach of trusting "just common sense".
> Only someone without kids would boil this down to a "single data point".
Why are you personalizing this? I have a family and have observed children grow from emergence from the womb and I grew in a much larger family. I'm not sure what the relevance is to the points being discussed. This seems like argument by anecdotal fallacy.
> I also deny that I have do anything to prove heritability, how about you prove the opposite?
I didn't ask you to prove anything. I asked you why you have no interest in looking at a scientific question beyond "I trust my own observations and my conclusion"?
And this question seemingly misses the point - it not a binary question about whether traits are inherited or not but about the degree of the role of inheritance. The author of the piece emphasizes this point extensively.
The salient point of the too-long article was about flaws in a seminal paper on this subject where the author Bouchard presented carefully collected data for identical twins - showing remarkably low variance suggesting a high degree of inheritance. But he hid the data he had collected for non-identical twins, which would have provided us with a basis for judging the significance of the findings regarding identical twins.
> It's a conclusion that is so obvious to the impartial mind that to be confused about it is a sign of extreme ideological indoctrination.
Can we just discuss the science and statistics here?
I was raised with five siblings, yet only I got into fights at school, and made my mother cry on a regular basis. Each of my sibs is similar and each of us is strikingly different, too.
As opposed to holding on to a belief that has been reinforced via personal experience countless times until very strong evidence proves otherwise. You end up with a set of beliefs that have a much higher chance of being true this way.
Or, confirmation bias gives a much higher chance of you believing so.
People fight and die over beliefs reinforced via personal experience. It's not proof against incorrectness.
Another thing is that sometimes it might be beneficial to believe something that isn't true. If you knew for a fact that tomorrow 99% of population will suffer extremely painful death then from the point of view of an individual the correct move would be to commit painless suicide, but the survival of humanity relies on everyone believing they'll be all fine. This is obviously a caricatural example, but there are lots of such lies that keep the society going, and "we're all equal" is just one of them.
Personally, I find it extremely difficult to believe that we'd be born equal, because evolution works only if some individuals are better than others, and I strongly believe that evolution is a thing.
No, we don't.
> I find it extremely difficult to believe that we'd be born equal
This is not what the article author claims or ever claimed.
The comment you wrote really isn't a response to anything this article said.
My father is adopted.
But now you hear nothing about this study. I'm not sure if it's because the results are tainted by eugenics, or if the techniques they developed were wrong...
Height, skin colour, sporting ability, body weight, eye colour, cancer risk, most disease risk, beauty.
Why would IQ be mostly random when other things are very heritable?
Occums razor says pick the simplest hypothesis that explains the data. The onus is on the blank slate crew to find some good data to demonstrate that IQ is not mostly heritable.
No one here, including the author linked, is suggesting what you propose.
The article is about how hard it is to tease these confounding factors apart. A highly intelligent parent is likely to prioritize their children's education. A hypothetical study that concludes "intelligent parents raise intelligent children" could easily be construed in favor of either the heriditarian or blank-slatist perspective.
https://archive.ph/6tOQF