Megafold: an Open-Sourced Alphafold-3 Training System
Posted3 months agoActive2 months ago
supercomputing-system-ai-lab.github.ioResearchstory
supportivepositive
Debate
10/100
AlphafoldProtein FoldingOpen-Source AIBioinformatics
Key topics
Alphafold
Protein Folding
Open-Source AI
Bioinformatics
The MegaFold project open-sources an AlphaFold-3 training system, sparking interest in the potential for community-driven advancements in protein folding research.
Snapshot generated from the HN discussion
Discussion Activity
Light discussionFirst comment
2h
Peak period
2
0-12h
Avg / period
1.5
Key moments
- 01Story posted
Oct 14, 2025 at 5:55 PM EDT
3 months ago
Step 01 - 02First comment
Oct 14, 2025 at 8:10 PM EDT
2h after posting
Step 02 - 03Peak activity
2 comments in 0-12h
Hottest window of the conversation
Step 03 - 04Latest activity
Oct 22, 2025 at 11:31 AM EDT
2 months ago
Step 04
Generating AI Summary...
Analyzing up to 500 comments to identify key contributors and discussion patterns
Discussion (3 comments)
Showing 3 comments
wynlla
2 months ago
Cool work!
shradhasehgal
3 months ago
Super interesting work. Wild that AF3 launched 100x more kernels. 768 tokens length training results seem cool.
uiuc-cs
3 months ago
great work!!
View full discussion on Hacker News
ID: 45585528Type: storyLast synced: 11/20/2025, 4:02:13 PM
Want the full context?
Jump to the original sources
Read the primary article or dive into the live Hacker News thread when you're ready.