Insights From Research with Probiotic E. Coli (2016)
Posted4 months agoActive4 months ago
pmc.ncbi.nlm.nih.govResearchstory
calmmixed
Debate
20/100
ProbioticsE. ColiMicrobiome Research
Key topics
Probiotics
E. Coli
Microbiome Research
The post shares insights from 2016 research on probiotic E. coli, sparking discussion on the potential risks associated with its use due to the production of genotoxins like colibactin.
Snapshot generated from the HN discussion
Discussion Activity
Light discussionFirst comment
2d
Peak period
1
54-60h
Avg / period
1
Key moments
- 01Story posted
Aug 22, 2025 at 3:10 AM EDT
4 months ago
Step 01 - 02First comment
Aug 24, 2025 at 12:58 PM EDT
2d after posting
Step 02 - 03Peak activity
1 comments in 54-60h
Hottest window of the conversation
Step 03 - 04Latest activity
Aug 24, 2025 at 12:58 PM EDT
4 months ago
Step 04
Generating AI Summary...
Analyzing up to 500 comments to identify key contributors and discussion patterns
Discussion (1 comments)
Showing 1 comments
hbplawinski
4 months ago
In more recent research, the E.coli Nissle strain was found to produce the genotoxin colibactin which is potentially linked to colorectal cancer (https://pubmed.ncbi.nlm.nih.gov/34378987/, among others). If this is a serious problem for the probiotic use is still unclear, but there is some research on how to replace it with a genetically modified strain that does not produce the genotoxin.
View full discussion on Hacker News
ID: 44981757Type: storyLast synced: 11/20/2025, 12:20:30 PM
Want the full context?
Jump to the original sources
Read the primary article or dive into the live Hacker News thread when you're ready.