Hpv Vaccination Reduces Oncogenic Hpv16/18 Prevalence From 16% to <1% in Denmark
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Denmark's HPV vaccination program has been a resounding success, slashing the prevalence of oncogenic HPV16/18 from 16% to less than 1%, and significantly reducing cervical cancer diagnoses. As commenters celebrated this achievement, some pointed out that the focus on cervical cancer has overshadowed the vaccine's benefits for men, including reduced risks of nasopharyngeal, penile, and rectal cancers. A lively debate ensued, with some users arguing that the conversation around HPV vaccination should expand to include its broader cancer prevention benefits, while others sparked controversy by linking promiscuity to health risks. Meanwhile, others noted that the development of next-generation vaccines against emerging strains is crucial, as the current vaccines may become less effective against evolving HPV types.
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I wonder if we'll those non-vaccine strains will eventually become the most prevalent.
Hope we'll develop vaccines against those too.
Ref: https://en.wikipedia.org/wiki/HPV_vaccine
HPV vaccination leads to massive reduction in nasopharyngeal, penile and rectal cancer in men.
The focus of messaging around HPV vaccination on ovarian cancer, female fertility and the age limitations for recommendations / free vaccination in some places are nothing short of a massive public health failure and almost scandal.
Just truthfully tell the boys their dicks might fall off and see how all of them quicklky flock to the vaccine.
Moral crusades have zero place in public health and are actively harmful.
HPV spreads through oral sex as well by the way.
It is a simple fact that unprotected sex with large numbers of people is very risky. We should have learnt that lesson in the eighties.
People don't want to hear this obviously. But it is a fact STI transmission has skyrocketed since the so called sexual revolution of the late sixties. Within fifteen years, we has an AIDS epidemic.
It’s the opposite of a fact. Gonorrhoea rates as an example rose significantly in the 1960s, but are now lower than in the 1940s and 1950s. This is thanks to good public health measures.
Start by making sure you’re accurately informed.
Those who marry younger are more likely to divorce. Or lead unhappy lives because they don't divorce to save face, but the marriage is dead.
The solution to covid/flu is wearing well-fitting masks and vaccines rather than never getting out.
The solution to STIs is good protection with vaccines, condoms and tests.
Religion can stay out of that.
Without the gays it might have gone a long time as a blood vector without being identified. When it was a "gay" disease it was busy killing old people who got transfusions but were never identified as having AIDS.
Every male above the age of 26 is locked out of the vaccine unless you pay out of pocket, which will be €300-€500 (or even higher).
For younger people it's three shots (second after two months, third after 6 months of the first one), now for older (over 30s or 40s, I can't remember exactly) it's recommended to get two shots (second after six months).
Statistically nobody even knows a guy who knows a guy who's dick fell off. Serious HPV problems for men are not even common enough to be viable urban legend. The nanosecond someone who took your bait shows up to be interviewed by some Youtube talking head about side effects the already severely damaged (compared to, IDK a decade ago) credibility of the medical establishment will go up in flames.
If nobody knows a guy who knows a guy who had penile cancer, that's probably because people are very bad about talking about genital health. I'm sure some of the men in my life have issues with erectile dysfunction, enlarged prostates, hemmorrhoids, etc. But no one is talking about those issues.
There's a reason old men crack jokes about prostate health, erectile dysfunction and incontinence rather than their dicks falling off and throat cancers.
I didn't say it wasn't a significant source of cancer. I said that nobody knows a guy who knows a guy who's dick fell off or some other extreme outcome. You need to be honest with people, not try and scare them like it's 1990 and DARE is the new hotness.
The public messaging you're trying to engage in could perhaps have skated by in a less critical time but in the current environment it will be counterproductive.
JFC. I'm checking out of this conversation.
Got a source?
So maybe 70% of throat cancer victims have HPV, and like 70% smoked - and if those were independent facts you'd expect that about 49% both smoked and had HPV, but it's actually more than half 'cos it turns out that if you have HPV then smoking is even worse. So that's nice.
[0] https://www.asha.org/practice-portal/clinical-topics/head-an...
Statistics are useless and/or misleading without context.
Citation needed.
A lot of people like him because he is a bully.
First answer and you directly go to 'racism', that's a rather poor effort. Put some more thought into your replies if you want to be taken seriously.
The government’s appalling failure wrt housing seems like a pretty valid reason for young people to distrust institutions tbh.
Then there are problems like the childcare benefits scandal ('toeslagenaffaire') - again partly related to migration by way of Bulgarian migrant fraud [4] - where the tax department made erroneous claims about benefit fraud without every really acknowledging they were wrong. I have some experience with the Dutch tax authorities making clear mistakes without accepting responsibility, instead they come up with mysterious restitutions which somehow exactly match the erroneously claimed taxes due.
The restrictive and SARS2 unpleasantness hit trust in public institutions hard which caused the universities of Rotterdam and Leiden to publish a report calling the Netherlands a new low-trust society ('de laag-vertrouwensamenleving', [6]). This trend has not reversed, especially among those with 'higher educational levels' [7] who used to have a higher trust in governmental institutions but now slid down to resemble the trust levels seen among those with 'lower educational levels' - this could simply be related to the fact that the left-wing parties favoured by those with 'higher education' did not participate in the government at that time.
I grew up in the Netherlands and lived there until about 25 years ago. I have seen this slide in trust with my own eyes, from the country where I could open the front door by pulling the string which dangled through the letter slot when I cycled home from school at 6 years old to the Fort-Knox-with-cameras now required, from the police officer on his bike greeting the people on his beat to "romeo's" (undercover arrest teams) being accused of inciting riots [8], from nearly the entire village coming out to welcome Sinterklaas (St. Nicholas who brings presents to children at the 5th of December) to those events being cancelled due to the fear of violence and protests, etcetera.
[1] https://www.volkshuisvestingnederland.nl/onderwerpen/huren-e...
[2] https://www.volkskrant.nl/binnenland/meer-sociale-huurwoning...
[3] https://iplo.nl/regelgeving/regels-voor-activiteiten/technis...
[5] https://en.wikipedia.org/wiki/Dutch_childcare_benefits_scand...
[6] https://www.impactcorona.nl/wp-content/uploads/2021/11/Def_-...
[7] https://www.scp.nl/actueel/nieuws/2025/03/04/onder-nederland...
[8] https://reportersonline.nl/politiegeweld-romeos/
That 'racism' word has lost its meaning due to severe overuse, find another argument. As to finding 'data', that is easy enough if you ask people around you. I live in Sweden and I hear this every day, everywhere, both in the countryside where I live as well as in the more urbanised areas on the west coast where I work and where my daughter goes to school.
If you want to get a bit closer to the actual truth than your knee-jerk 'racism' accusation you should look into the clash of cultures - not races - which lies at the bottom of these problems. Go and speak to people from low-trust societies as well as those from high-trust societies and ask them where they put their trust, how they think about their neighbours - not just the ones in the house next door but also those in other areas.
https://x.com/jonatanpallesen/status/1993654135917257214/pho...
One would have to be crazy in order to extend exactly the same trust towards a random Danish Dane vs. a random Somali Dane.
Not every negative statement about non-white people is rooted in racism, and the ugly, fanatical attitude "everyone who has a negative observation about any sort of immigrants must be racist, stupid and evil" is what upended the political spectrum and brought the far right to power in many places.
We all need something like ranked/list voting and incorporate invalid votes into the result so urgently.
If you want full privacy you’d get no notifications and would have to go and ask for various things which you many not know exist.
What makes it work is the public registers.
e-boks is like gmail (and others) in that it keeps your old mail. So you can easily find old stuff, a great improvement on paper mail.
I don't even check my physical mailbox once a week.
Denmark is one of the very most digital countries. Physical mail is very much on the way out. We no longer has mailboxes to send mail, you have to go to a shop to send letters, which now cost at last $6 per letter due to the low amount of mail sent.
It is only a matter of less than 10 years before letters will be fully gone.
As number of deliveries per address drops, the delivery costs trend towards the same price as small package delivery.
Which is bad, we definitely should have them. Referral data appears to be managed through Healthlink, which may just be a privatised not always used medical record system.
This is bad (from my perspective, as someone who's moved a lot and thus has medical records scattered all over).
> It will be a no-opt-out centralised EHR and combined social care record.
This is probably the right approach, even though I'm sceptical that it will be delivered effectively.
While we have some anivaxxers here in DK, most people (90%, I believe) are sane and follow the recommendations.
The vaccinations start while the children are small and continue while they grow up .. the last one is when they are 12.5 years old.
The notifications are delivered in eboks or by mail if you don't want to use eboks. Everything from the state is delivered like this. There is nothing special about how the information is delivered. The SMS/e-mail notifications are just about how sent you something and not about what it is. At least for me.
I don't see how the use of eboks makes this work better. It would work just as well without eboks. People listen to doctors and the MAGA like shitheads we do have don't have a lot of influence.
Those are basic bits of knowledge that apply to most vaccinations.
The problem is that the quacks diminish the positive effects, exaggerate the negatives and engage in a campaign of fear mongering that costs some people (and in some cases lots of people, see COVID) their lives. They are not only clueless, they are malicious.
From Gwyneth Paltrow, JFK Jr, all the way to Donald Trump and a whole raft of others the damage is immense. I have a close family member who now is fully convinced of the healing power of crystals and there isn't a thing you can do to reason with people that have fallen into a trap like that.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6288961/
This has nothing to do with vaccines. There is a very good reason that misinformation is, and should remain legal. This simply allows the person or group who gets to define what is or is not misinformation to arbitrarily imprison anyone doing publishing they don’t like.
Maybe I did?
It is possible that we just disagree on this. Clearly misinformation about medical stuff is so damaging that many places have found it necessary to have laws on the books. I'm just elevating this from a misdemeanor to an actual crime based on the outcomes.
That scientific consensus you are alluding to is not what you claim it was.
Finally, we're talking about celebrities without any qualification whatsoever spreading utter nonsense causing real harm, you can look at that in isolation and compare it to you making that statement out of an abundance of caution regarding something where there is no downside. The two simply are not equivalent. Free speech absolutists always pull the same trick, aiming to refuse an obvious wrong in order to defend their bastion while forgetting that there isn't a black-or-white at all, you can have some reasonable limits on what people can and can not do and in the age of 'influencers' with global reach the danger is much more prevalent than it used to be.
Free speech is a great good, but it is not the greatest good.
The dangers of medical misinformation, regardless of scale, do not negate the fact that criminalizing _what the state calls_ misinformation allows the state to arbitrarily imprison people publishing things, because it demands that the state be the arbiter of truth, something that does not have an objective legal method of determination. If it somehow did, promoting religion would of course be illegal as it is clear misinformation.
Also, consider for a moment the insane amount of harm the delusion that is religious belief has wrought. Should we be outlawing that, too? The suggestion that prayer is an effective treatment for ailments is a claim they have been making for millennia. Shall we somehow square your anti-misinformation law with religious freedom?
People should always be free to be wrong, because we often don’t know what is right until many decades or centuries or millennia later.
Dishonest practices and claims to have special knowledge and skill in some field, typically medicine.
The legal definition does not require one to first be a licensed doctor.
And malpractice is definitely not covered by freedom of speech.
Not everybody lives in the USA.
My medical insurance will pay for several literally fake/quack treatments because of this crap. If you want to wage war against Quackery I better see you going after "big Chiropractor" first.
Your comparison of Sweden vs Austria has a problem: Covid did more damage in warmer climates. Thus this proves nothing about policy. Look to others more similar--Sweden didn't fare well.
Hmm. Compared to what measurement? Most viruses are actually not oncogenic.
From cancer causes, oncogenic viruses are thought to be responsible for about 12% of human cancers worldwide:
https://www.mdpi.com/2079-7737/14/7/797
From what I remember, most viruses are not oncogenic in nature, so I am unsure whether the statement made is correct.
E.g. EBV is strongly associated with several lymphomas.
There are other significant clinical associations for HPV, HBV, HCV, HTLV-1, HHV-8, and many others.
https://www.midwesterndoctor.com/p/the-perils-of-vaccinating...
Interested to hear evidence-based counterarguments to what is laid out in the article.
Citation needed. In Germany, the HPV vaccine is recommended only to below 14 year olds, so as to reduce precisely that risk.
https://www.rki.de/SharedDocs/FAQs/DE/Impfen/HPV/FAQ-Liste_H...
For the HPV section specifically, there were at least two major omissions.
First, in his table showing autoimmune adverse effects, he has chosen to crop out the next column in the table containing the control conditions - which show very similar rates of adverse effects to the vaccine condition.
Secondly, when discussing negative efficacy in the case of existing persistent infection, he only quotes the data from one of three studies that the linked report covers. The linked report indeed covers the negative efficacy in study 013 as an area of concern. However, study 015 (which had roughly twice the number of total participants as study 013) showed no real evidence of negative efficacy. When all 3 studies are pooled together, the point estimate still says negative efficacy, (at ~-12%), however the error bars are quite wide.
Why this is tragic, is because these two omissions do actually point to failures in public communication about the vaccine. For example, the control condition in the Merck trials were a mix of saline injections (this is the traditional placebo), as well as injections with just the adjuvant (AAHS). This is less standard, and raises legitimate questions about why Merck used an adjuvant as the control, instead of just saline. There a cynical/conspiratorial angle to this question, which I think would be directionally correct.
The second omission is because I think there is a reasonable question of "are there extra risks associated with getting the HPV vaccine while having an active persistence infection", even when taking into account the different and larger study populations within the original trial data. Once again, I think the idea that both companies and public health agencies don't want to deal with a vaccine that requires testing before hand is true. I also believe that on a population level, even if there was a modest increase in risk in that specific subgroup, it makes sense to implement broad vaccination campaigns.
That said, I think the unwillingness of public health agencies to engage with this tricky area of communication and education creates these types of opening for anti-vaccine messaging. If you want a sense of "conspiracy" - here's a random review study - https://pmc.ncbi.nlm.nih.gov/articles/PMC8706722/
Notice that when reporting results, the groupings for HPV status at enrollment time are "naive" and "irrespective" - the "test positive" grouping isn't broken out.
So I'm fine with it being flagged and decline to vouch for it.
In this house we believe Love is love Black Lives Matter Science is real Feminism is for everyone No human is illegal Kindness is everything
Signaling your alignment to the public-facing opinions of your social betters is the modern ersatz religion for atheists. The television is the temple, the pundits the priests. Apostates and heretics are not welcome here. Now, my child, you would not want your words to inadvertently cause the faithful to stray. Would you? Just think of what the late night comedians would say if they could hear you cast doubt on their sponsor Pfizer? Perhaps you would rather join our hate session on the pagans in flyover country?
- HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain.
- Sooner is better, but vaccination can be done at any age: Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects against different strains and reinfection. See: https://pubmed.ncbi.nlm.nih.gov/38137661/
- HPV16 is responsible for a large number of throat cancers: This affects both men and women. Vaccinating men is important for their own safety and to reduce transmission to their partners.
You can get HPV without sex too.
https://www.cdc.gov/sti/about/about-genital-hpv-infection.ht...
"HPV is most commonly spread during vaginal or anal sex. It also spreads through close skin-to-skin touching during sex"
This focuses on sex, but any virus that can be found on skin, also has a chance to be transmitted without sex just as well. Admittedly the chance here for HPV infection is much higher with regard to sex, but not non-zero otherwise. The HeLa cells also contain a HPV virus in the genome, though this was probably transmitted via sex:
"The cells are characterized to contain human papillomavirus 18 (HPV-18)"
HPV-18. I think HPV-18 may in general be more prevalent than HPV-16.
https://www.sciencedirect.com/science/article/pii/S277270762...
So, NOT in fact “just as well”.
However, the vaccination is expensive (~1k) and it is difficult to find doctors who will do non-recommended vaccinations for self-payers.
YCMV
Depends entirely on where you are and what your healthcare situation is. Mine cost me ~100eur.
(even for rest-of-the-world topics)
I am currently getting the HPV series and I only had to pay my copay for the first appointment have nothing for the second one (I am assuming it will be the same for the third)
I wish more people would get vaccinated.
1) if you've ever been exposed to HPV already, then the vaccine is useless
2) there is no test to determine if a male has been exposed, although there is one for females
so they just push the ages up by probability, over time. As the probability of a man being with an older and therefore unvaccinated woman decreases - since with women is the most probable - the age can rise
It is incorrect. I had it tested multiple times. It is done less routinely, usually under assumption that since it is women who are mostly at risk, why bother testing men. Which is horrible mindset in anything related to epidemiology.
See:
- https://www.droracle.ai/articles/607248/what-methods-are-use...
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12256477/
- https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2...
It's also not actionable.
Sure, it has lower specificity and sensitivity that for women, but it is not binary - works or not. Life is probability, and it is a huge fallacy to believe that things work 100% or 0%, nothing in between (rarely the case in medicine).
It IS actionable on many ways. Most important, screening for female partners, informed risk for partners or your on safety for ones partners (condoms BTW reduce infection rates, but do not fully protect, as HPV can be on other parts of skin).
and even if it is reliable, its utility is limited
all leads to focusing solely on probability of exposure(s)
I think the most insightful thing is that there are 9 HPV variants some of which someone wouldn't have exposure to so its worthwhile to get the vaccine anyway
but other than that, the situation is the same. for men's age the utility of the vaccine is based on probability alone, as its a waste of resources to even attempt checking for prior/current exposure
This is patently incorrect. The vaccine protects against 9 variants. Having been exposed to all 9 before vaccination sounds like really bad luck.
> 2) there is no test to determine if a male has been exposed, although there is one for females
The female HPV tests, as I understand, only test for the presence of HPV in the cervix. It can be present in many other areas. No one is testing women for the presence of HPV on their hands or in their throats.
Most places now offer HPV vaccines to young boys as well. People over 40 more or less missed the boat, but they can still get vaccinated. How useful it is depends entirely on their personal circumstances and risk profiles.
Why is this different? Why is pestering a doctor to give me a medicine they don't recommend a good idea?
Kind of hurts my pride, but seeing as I'm older than 40, and my wife and I are pretty freaking boring, the vaccine is better spent on someone with more opportunities ahead of them.
I really hate these vaccine specific awareness campaigns. Not only do they hurt my vanity, but I know too many people who are anti-vaxers, or into weird fake medicines.
I just go with what my doctor says. If social media says something different, social media is wrong.
But really, don’t get your vaccine schedule from Hacker News.
The activists on these threads should probably be pushing folks to get their kids vaccinated.
Doctors/medical associations don't agree with each other on much, even at the very highest levels. For example, the USA and EU have totally different recommendations related to digital rectal exams for aging men. One believes that finding cancer in old men is important, the other claims it's bad because most of those cancers are benign and sticking a finger up an old mans butt often causes its own complications.
Doctors are not all knowing, infallible oracles. They are human beings you can have a conversation with about your health. If you think something makes sense for you, you can run it past them. No one is suggesting randomly asking doctors to prescribe random shit.
In the 1960s, more than 900 people were diagnosed with cervical cancer each year, corresponding to more than 40 cases per 100,000 Danes.
Today, that number is below 10 per 100,000 nationwide – and among women aged 20 to 29, only 3 out of 100,000 are affected. This is below the WHO’s threshold for elimination of the disease.
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