Eye Drops Could Replace Glasses or Surgery for Longsightedness, Study Says
Posted4 months agoActive4 months ago
theguardian.comResearchstory
calmmixed
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Eye CareMedical ResearchVision Correction
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Eye Care
Medical Research
Vision Correction
A new study suggests that eye drops containing pilocarpine and naproxen could potentially replace glasses or surgery for longsightedness, sparking discussion about the technology's potential benefits and limitations.
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I mildly dislike wearing glasses but need them or I have a headache within an hour, I can’t overcome my blink reactions to put in contacts (after several hour long sessions with my optometrist) and my shortsightedness isn’t strong enough to convince myself to go for laser eye surgery.
Easiest link I found: https://news.ycombinator.com/item?id=44938818
Not something that is recommended for ordinary bad vision - as it mostly works to treat eye pressure (one particular type of age related vision correction).
I always think about it from the point of view of what would happen if I want to do extended travel. Which method minimizes risk around something going wrong.
For example:
If you put your contacts in luggage and that gets lost or stolen now you have a really big problem with your sight in a foreign country.
If you're dependent on drops, it's the same problem as contacts.
In both cases, even if you do things to minimize losing them they have a limited supply. What if you want to travel for a year, are you comfortable getting the same type you have at home sent to you in a foreign country?
If you're dependent on glasses, typically you wear them all the time so the risk is them getting broken somehow which is rare. I've been wearing glasses my whole life and have never once broke or damaged them. The biggest risk is falling asleep with them on and rolling over them so it's critically important to move them off to the side somewhere. That also means being extra careful if you're sleeping on a bus or outdoors, you need to be really mindful of where your glasses are at all times if you're not wearing them.
The downside to glasses is they can prevent you from experiences. Casual swimming is annoying, especially alone where you also want to watch your bag that could be hundreds of feet away. Also practicing martial arts with sparring is a problem. Showering without being able to see clear isn't too bad in practice but it's a daily thing.
Surgery has the highest potential upside since you effectively become "normal" but the surgery has to go well so there's a risk factor to think about now. I only know 3 people who have gotten lasik in the last ~15 years. 1 of them sees massive halos at night time with lights so they can't drive at night. 1 of them has to use eye drops for dryness even 2 years after surgery. 1 of them had it done about 10 years ago and has no negative side effects but the effects of the surgery are slowly wearing off to where they will need another surgery in the next few years since their eyes have changed.
Personally if I knew surgery had a 99.999% side effect free success rate and at worst I would only need to do it every 10-15 years I would do it but I just can't get past the risk factor. Sight is just too important. I look forward to a day where this is a fully solved problem in a non-invasive way.
Until then I compromise with glasses.
Then again, my eyesight isn't bad enough for me breaking my glasses on a holiday to be a potential problem. I've never broken any of my pairs before, and even if they were lost, I'm still able to read and get around. It's just more unpleasant to do so. But I still prefer glasses and wear them pretty much at all times.
In my case I worked onboard tall ships. Contacts let me be on deck in inclement weather without worrying about spray, fog, or losing a pair of glasses, let me use any pair of sunglasses instead of a ~$250+ pair of prescription glasses, as well as things like diving and snorkelling without needing a $150 prescription mask.
I wear contacts in water or if I lose my glasses, but try to use glasses most of the time to let my eyes breathe.
This actually happened to me. Spent two months on the other side of the planet. When I landed I realized I didn't pack my contacts. I just wore the same pair the whole time and was fine.
When you wore yours for 2 months, what type was it?
I talked to my optometrist and they told me that most contacts are the same material, and bi-weeklies/etc are just slightly thicker for durability.
I was diligent about cleaning them, while at the same time being gentle so I didn't tear them. I was also very cautious about swimming with them, touching them or otherwise doing anything that might promote eye infections. Comfort-wise, they were fine, but it felt like they shrank slightly over time, if that makes sense.
I got sick of the daily ritual of having to clean my hands, put them in and then take them out at night.
My eyesight was pretty bad with a large prescription and keratoconus on top (that I did have C3R surgery for). I was dismayed when I found out I wasn't eligible for laser surgery so I just accepted that I'd have to deal with the inconvenience of glasses/lenses during the most active years of my life.
Then I found out that you can do Refractive Lens Exchange (same surgery that they do for people with cataracts) and went for that a few years ago. It isn't perfect but - for me at least - it was worth the risk. I do get issues with glares when it's dark but when it's bright there are no side effects. I also had to get a YAG laser treatment about a year later due to some 'clouding' but that not a big deal other than the expense.
When I last went for an eye test I was told I had 20/20 vision in one eye and I didn't believe the optician. I've long forgotten what 20/20 vision is like so maybe it's just overrated.
I can also never get cataracts!
LASIK/SMILE/etc were never and are not safe. At least ICL is fully reversible.
Note that is the current version (EVO) I’m referring to, not the older (Visian) which still involved irreversible steps.
Info: https://eyewiki.org/Implantable_Collamer_Lens
Patient info (simpler language): https://www.rcophth.ac.uk/wp-content/uploads/2020/05/Phakic-...
(I paid out of pocket for this and have no affiliation with any clinics)
Citation needed.
All people I know and feedback I've heard that took LASIK or LASEK have said that it was a live-changing surgery. I myself underwent LASEK and have nothing bad to say.
I've never heard that it was unsafe. Quite the opposite, actually.
Then again, when I hear feedback from Americans it sounds like a different world. I live in a wealthy and medically-respected European country, though.
Basically, contact lenses you wear at night (which could perhaps be tolerable for you). Then, your vision stays fine during the day (mostly, it worsens gradually but it's manageable).
I don't use it myself but I have a relative that does and they love it.
https://en.wikipedia.org/wiki/Orthokeratology
It wasn't a slow decline. One day my eyes worked like they had for my entire life, and the next my eyes went wonky. Getting older sucks! Without glasses, I can still read books and my phone just fine. I've just lost my "middle vision" of about an arm's length away.
Anyways, all my fifty-something peers are going through the same thing. It's a really inconvenient life change. I imagine something like this would be popular if it were more well known. My optometrist didn't say anything at all about it.
Side note: Laser surgery can only fix one type of vision problem. So if I were to go in to fix my myopia, I'd still have presbyopia (age related hyperopia), or vice versa. There doesn't seem to be a one-size-fits-all surgery for vision.
since you can only see a short distance ahead.
They just started human testing after years of doing and redoing their solution. I assume they're being somehow paid by the industry not to release too early, because even the first iteration had great results and it would have been life changing.
Hopefully this is not another RISUG and we see some innovation reach the market.
It seems that this formulation differs by adding naproxen, an NSAID. I'm not sure why they believe this is needed.
[1] https://news.ycombinator.com/item?id=29509163
I wonder if using that might be dangerous for people with people with conditions that could lead to macular damage ... (by adding pressure)