AI Antibody Design in 2025

Posted3 months ago

harleyk

4 points

1 comments

blog.booleanbiotech.comResearchstory

calmpositive

Debate

10/100

AI in HealthcareAntibody DesignBiotechnology

Key topics

AI in Healthcare

Antibody Design

Biotechnology

The article discusses the advancements and potential of AI in antibody design by 2025, with the HN community showing interest but limited engagement.

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01Story posted
Sep 29, 2025 at 5:06 PM EDT
3 months ago
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Sep 29, 2025 at 5:06 PM EDT
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Sep 29, 2025 at 5:06 PM EDT
3 months ago
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harleykAuthor

3 months ago

Antibodies are proteins, so why is antibody design not just the same problem as mini-binder design? In most ways they are the same. The main difference is that the CDR loops that drive antibody binding are highly variable and do not benefit directly from evolutionary information the way other binding motifs do. Folding long CDR loops correctly is especially difficult.

Here I'll review the latest antibody design tools.

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ID: 45418761Type: storyLast synced: 11/17/2025, 12:06:15 PM

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