How Quickly Mrna Degrades Is Linked to Autoimmune Disease Risk
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Mrna DegradationAutoimmune DiseaseGenetic ResearchImmunology
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Mrna Degradation
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Research suggests a link between the rate of mRNA degradation and the risk of autoimmune diseases, with potential implications for understanding disease mechanisms and developing treatments.
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> The team also found that several of the genetic variants linked to unstable mRNA had already been associated with autoimmune diseases in large-scale genetic studies.
> [...]
> Using additional modeling, the researchers linked expression levels of these stability-regulated genes to diseases including allergic rhinitis, lupus, diabetes mellitus and multiple sclerosis.
Anyone here familiar with mRNA-targeted pharmacology? Even if "take this pill" only worked for 10% of those afflicted with such disorders, that'd still be a huge reduction in human suffering.